Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
degQExported protease; Similar to Escherichia coli protease degq precursor degq or hhoa or b3234 SWALL:DEGQ_ECOLI (SWALL:P39099) (455 aa) fasta scores: E(): 9.7e-110, 70.67% id in 457 aa; Belongs to the peptidase S1C family. (456 aa)    
Predicted Functional Partners:
rseA
sigma-E factor negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases [...]
  
 
 0.824
fkpA
Similar to Escherichia coli fkbp-type peptidyl-prolyl cis-trans isomerase FkpA precursor FkpA or b3347 SWALL:FKBA_ECOLI (SWALL:P45523) (270 aa) fasta scores: E(): 9.4e-63, 73.13% id in 268 aa.
   
 
 0.763
ompA
Outer-membrane protein A; Similar to Erwinia carotovora putative outer-membrane protein a precursor OmpA SWALL:Q9RM69 (EMBL:AJ249340) (367 aa) fasta scores: E(): 2.6e-120, 90.32% id in 372 aa, and to Serratia marcescens outer membrane protein a precursor OmpA SWALL:OMPA_SERMA (SWALL:P04845) (359 aa) fasta scores: E(): 4.8e-71, 75.61% id in 369 aa; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
   
 
 0.738
ecfK
Putative surface antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
  
   
 0.692
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
  
  
 0.626
degS
Exported protease; Similar to Escherichia coli, and Escherichia coli O157:H7 protease DegS precursor DegS or HhoB or HtrH or b3235 or z4594 or ecs4108 SWALL:DEGS_ECOLI (SWALL:P31137) (355 aa) fasta scores: E(): 9.1e-73, 58.51% id in 364 aa.
 
    
0.578
pspC
Phage shock protein C; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri phage shock protein C PspC or b1306 or c1777 or z2479 or ecs1883 or sf1311 SWALL:PSPC_ECOLI (SWALL:P23855) (119 aa) fasta scores: E(): 1.5e-25, 63.15% id in 114 aa.
 
  
 0.578
lon
ATP-dependent protease la; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
    
 0.576
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.556
surA
Survival protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
     
 0.556
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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