STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nudFADP-ribose pyrophosphatase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri ADP-ribose pyrophosphatase NudF or b3034 or c3780 or z4391 or ecs3922 or sf3074 SWALL:ADPP_ECOLI (SWALL:P36651) (209 aa) fasta scores: E(): 8.2e-61, 79.1% id in 201 aa. (210 aa)    
Predicted Functional Partners:
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.907
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
    
  0.904
pgm
Phosphoglucomutase; Similar to Escherichia coli phosphoglucomutase Pgm or b0688 SWALL:PGMU_ECOLI (SWALL:P36938) (546 aa) fasta scores: E(): 5e-188, 87.72% id in 546 aa.
   
 
 0.904
nudE
Similar to Escherichia coli ADP compounds hydrolase NudE or b3397 SWALL:NUDE_ECOLI (SWALL:P45799) (186 aa) fasta scores: E(): 2.1e-54, 76.75% id in 185 aa.
     
  0.900
ECA0332
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YqiB SWALL:AAN44551 (EMBL:D16557) (140 aa) fasta scores: E(): 1.6e-47, 80% id in 140 aa.
 
    0.885
nnrE
Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]
  
 0.731
birA
Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
   
    0.559
tolC
Similar to Escherichia coli outer membrane protein TolC precursor TolC or MtcB or MukA or RefI or b3035 SWALL:TOLC_ECOLI (SWALL:P02930) (495 aa) fasta scores: E(): 4.1e-124, 75.32% id in 466 aa, and to Erwinia chrysanthemi outer membrane protein TolC SWALL:Q93AG1 (EMBL:AF421372) (472 aa) fasta scores: E(): 2.3e-128, 77.89% id in 466 aa.
 
 
   0.535
ECA0334
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YqiA SWALL:YQIA_ECOLI (SWALL:P36653) (193 aa) fasta scores: E(): 5.8e-60, 75.78% id in 190 aa.
     
 0.503
icc
cAMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
     
 0.447
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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