STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0332Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YqiB SWALL:AAN44551 (EMBL:D16557) (140 aa) fasta scores: E(): 1.6e-47, 80% id in 140 aa. (144 aa)    
Predicted Functional Partners:
nudF
ADP-ribose pyrophosphatase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri ADP-ribose pyrophosphatase NudF or b3034 or c3780 or z4391 or ecs3922 or sf3074 SWALL:ADPP_ECOLI (SWALL:P36651) (209 aa) fasta scores: E(): 8.2e-61, 79.1% id in 201 aa.
 
    0.885
rsd
Regulator of sigma D; Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
  
     0.656
ECA0090
Similar to Yersinia pestis hypothetical protein ypo4065 SWALL:AAM87627 (EMBL:AJ414160) (118 aa) fasta scores: E(): 6.1e-24, 67.52% id in 117 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YibL SWALL:YIBL_ECOLI (SWALL:P36564) (120 aa) fasta scores: E(): 2.8e-21, 63.63% id in 121 aa.
  
     0.614
ompX
Outer membrane protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri outer membrane protein X precursor OmpX or b0814 or c0900 or z1036 or ecs0892 or sf0765 SWALL:OMPX_ECOLI (SWALL:P36546) (171 aa) fasta scores: E(): 9.1e-40, 66.47% id in 173 aa.
  
     0.574
ECA1013
Putative lipoprotein; Similar to Escherichia coli, and Escherichia coli O6 hypothetical lipoprotein ygdi precursor ygdi or b2809 or c3380 SWALL:YGDI_ECOLI (SWALL:Q46924) (75 aa) fasta scores: E(): 1.6e-14, 61.11% id in 72 aa, and to Shigella flexneri orf, conserved hypothetical protein ygdi or sf2823 SWALL:AAN44310 (EMBL:AE015296) (76 aa) fasta scores: E(): 4.2e-14, 59.72% id in 72 aa.
  
     0.562
ECA0334
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YqiA SWALL:YQIA_ECOLI (SWALL:P36653) (193 aa) fasta scores: E(): 5.8e-60, 75.78% id in 190 aa.
 
     0.561
ECA4182
Similar to Yersinia pestis hypothetical protein ypo3844 or y0386 SWALL:Q8ZAF8 (EMBL:AJ414159) (234 aa) fasta scores: E(): 1.8e-68, 73.93% id in 234 aa, and to Salmonella typhi hypothetical protein Sty3611 SWALL:Q8Z3A7 (EMBL:AL627279) (235 aa) fasta scores: E(): 4.6e-60, 64.68% id in 235 aa.
  
     0.546
ECA3587
Putative membrane protein; Similar to Yersinia pestis putative exported protein ypo0651 or y3528 SWALL:Q8ZI63 (EMBL:AJ414144) (207 aa) fasta scores: E(): 2.5e-57, 76.69% id in 206 aa, and to Salmonella typhimurium, and Salmonella typhi putative sh3 domain protein ygim or stm3203 or sty3382 SWALL:Q8XFH7 (EMBL:AE008847) (204 aa) fasta scores: E(): 1.4e-51, 71.84% id in 206 aa.
  
    0.545
ECA0033
Putative GNAT-family acetyltransferase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YiiD SWALL:YIID_ECOLI (SWALL:P32148) (329 aa) fasta scores: E(): 1.6e-108, 82.31% id in 311 aa, and to Salmonella typhimurium, and Salmonella typhi putative acetyltransferase YiiD SWALL:Q8XF59 (EMBL:AE008888) (329 aa) fasta scores: E(): 2.7e-107, 81.34% id in 311 aa.
  
    0.533
sdhE
Conserved hypothetical protein; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
  
     0.506
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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