STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0336LysR-family transcriptional regulator; Similar to Neisseria meningitidis CrgA SWALL:Q9JPU9 (EMBL:AF190471) (299 aa) fasta scores: E(): 4.9e-49, 45.27% id in 296 aa, and to Yersinia pestis LysR-family regulatory protein ypo0669 or y3510 SWALL:Q8ZI45 (EMBL:AJ414144) (303 aa) fasta scores: E(): 1.4e-70, 65.18% id in 293 aa; Belongs to the LysR transcriptional regulatory family. (298 aa)    
Predicted Functional Partners:
sftR
LysR-family transcriptional regulator; Similar to Pseudomonas putida SftR SWALL:Q9WWU4 (EMBL:AF126201) (304 aa) fasta scores: E(): 1.2e-43, 42.19% id in 301 aa, and to Pseudomonas sp. SDS degradation transcriptional activation protein sdsB SWALL:SDSB_PSES9 (SWALL:P52686) (306 aa) fasta scores: E(): 1.3e-30, 36.53% id in 312 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.731
nac
Partial CDS. Similar to the N-terminal region of Escherichia coli nitrogen assimilation regulatory protein Nac or b1988 SWALL:NAC_ECOLI (SWALL:Q47005) (305 aa) fasta scores: E(): 1.4e-23, 77.77% id in 90 aa.
  
     0.675
ECA3202
LysR-family transcriptional regulator; Similar to Ralstonia solanacearum probable DNA-binding transcriptional regulatory transcription regulator protein rsc1196 or rs05728 SWALL:Q8Y048 (EMBL:AL646063) (306 aa) fasta scores: E(): 3.9e-42, 42.76% id in 297 aa, and to Brucella melitensis transcriptional regulatory protein, LysR family bmeii1077 SWALL:Q8YB24 (EMBL:AE009740) (294 aa) fasta scores: E(): 2.7e-38, 39.51% id in 291 aa.
  
     0.653
parE
Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
     
 0.645
ECA2642
Similar to Pseudomonas putida transcriptional regulator, LysR family pp4522 SWALL:AAN70096 (EMBL:AE016791) (297 aa) fasta scores: E(): 5.6e-24, 29.64% id in 280 aa, and to Rhizobium loti transcriptional regulator mlr6990 SWALL:Q987M7 (EMBL:AP003010) (299 aa) fasta scores: E(): 4.7e-18, 30.45% id in 266 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.641
hdfR
LysR-family transcriptional regulator; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
     0.596
ECA0610
Similar to Pseudomonas putida transcriptional regulator, LysR family pp5261 SWALL:AAN70826 (EMBL:AE016793) (308 aa) fasta scores: E(): 3.6e-24, 32.4% id in 287 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 glycine cleavage system transcriptional activator GcvA SWALL:GCVA_ECOLI (SWALL:P32064) (305 aa) fasta scores: E(): 2.4e-16, 31.13% id in 273 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.477
cbl
Similar to Escherichia coli transcriptional regulator Cbl or b1987 SWALL:CBL_ECOLI (SWALL:Q47083) (316 aa) fasta scores: E(): 2.1e-84, 70.34% id in 317 aa, and to Klebsiella aerogenes transcriptional regulator Cbl SWALL:CBL_KLEAE (SWALL:Q08598) (316 aa) fasta scores: E(): 2.5e-85, 71.92% id in 317 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.476
ECA1965
Similar to Pseudomonas aeruginosa probable transcriptional regulator pa5179 SWALL:Q9HU10 (EMBL:AE004931) (293 aa) fasta scores: E(): 4.3e-38, 41.33% id in 300 aa, and to Pseudomonas putida transcriptional regulator, LysR family pp4601 SWALL:AAN70174 (EMBL:AE016791) (295 aa) fasta scores: E(): 2e-34, 37.91% id in 298 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.463
icc
cAMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
       0.458
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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