STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0350Similar to Yersinia pestis putative iron-containing alcohol dehydrogenase ypo0678 SWALL:Q8ZI38 (EMBL:AJ414144) (385 aa) fasta scores: E(): 3.8e-112, 76.94% id in 386 aa, and to Escherichia coli hypothetical oxidoreductase YqhD SWALL:YQHD_ECOLI (SWALL:Q46856) (387 aa) fasta scores: E(): 3e-108, 73.64% id in 387 aa. (387 aa)    
Predicted Functional Partners:
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
  
 
 0.951
gldA
Glycerol dehydrogenase; Similar to Escherichia coli, and Escherichia coli O6 glycerol dehydrogenase GldA or b3945 or c4904 SWALL:GLDA_ECOLI (SWALL:P32665) (367 aa) fasta scores: E(): 1.2e-57, 49.16% id in 358 aa.
     
 0.947
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
    0.862
ECA0351
Probable nitroreductase; Similar to Bacillus subtilis nitro/flavin reductase NfrA or NfrA1 or Ipa-43D SWALL:NFRA_BACSU (SWALL:P39605) (249 aa) fasta scores: E(): 5.2e-19, 29.83% id in 248 aa, and to Clostridium acetobutylicum ortholog ycnd b.subtilis, nitroreductase cac0718 SWALL:Q97L47 (EMBL:AE007587) (246 aa) fasta scores: E(): 1.2e-42, 45.49% id in 244 aa; Belongs to the flavin oxidoreductase frp family.
  
    0.786
dkgA
Similar to Escherichia coli 2,5-diketo-D-gluconic acid reductase A DkgA or b3012 SWALL:DKGA_ECOLI (SWALL:Q46857) (275 aa) fasta scores: E(): 1e-80, 72.42% id in 272 aa. In Salmonella typhi this is a putative pseudogene but it is apparently intact here.
  
 
 0.726
adhE
Aldehyde-alcohol dehydrogenase; Similar to Escherichia coli, and Escherichia coli O157:H7 aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase, acetaldehyde dehydrogenase, and pyruvate-formate-lyase deactivase AdhE or Ana or b1241 or z2016 or ecs1741 SWALL:ADHE_ECOLI (SWALL:P17547) (890 aa) fasta scores: E(): 0, 89.1% id in 890 aa; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.607
ECA2346
Similar to Salmonella typhi putative oxidoreductase sty1828 SWALL:Q8Z6F0 (EMBL:AL627271) (285 aa) fasta scores: E(): 1.1e-72, 63.7% id in 281 aa, and to Escherichia coli hypothetical protein yeae yeae or b1781 SWALL:YEAE_ECOLI (SWALL:P76234) (284 aa) fasta scores: E(): 4.1e-72, 63.7% id in 281 aa.
  
 
 0.538
ECA0352
Similar to Yersinia pestis AraC-family regulatory protein ypo0679 SWALL:AAM87046 (EMBL:AJ414144) (297 aa) fasta scores: E(): 3.2e-77, 66.21% id in 296 aa, and to Escherichia coli hypothetical transcriptional regulator YqhC SWALL:YQHC_ECOLI (SWALL:Q46855) (318 aa) fasta scores: E(): 1.2e-66, 57.77% id in 296 aa.
     
 0.499
ECA3762
Similar to Escherichia coli O6 putative alcohol dehydrogenase c0762 SWALL:Q8FJW8 (EMBL:AE016757) (385 aa) fasta scores: E(): 1.1e-83, 61.96% id in 376 aa, and to Agrobacterium tumefaciens AttL SWALL:Q8VPD6 (EMBL:AY052389) (399 aa) fasta scores: E(): 4.6e-36, 35.84% id in 371 aa.
  
  
0.487
ECA3005
Similar to Ralstonia solanacearum putative glutamine amidotransferase protein rsc0213 or rs00645 SWALL:Q8Y2W9 (EMBL:AL646058) (238 aa) fasta scores: E(): 9e-37, 45.37% id in 238 aa, and to Xylella fastidiosa GMP synthase xf0560 SWALL:Q9PFU7 (EMBL:AE003903) (240 aa) fasta scores: E(): 1.1e-28, 43.8% id in 242 aa.
  
    0.474
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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