Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
scrKFructokinase; Similar to Escherichia coli fructokinase CscK SWALL:SCRK_ECOLI (SWALL:P40713) (307 aa) fasta scores: E(): 4.5e-67, 60.39% id in 303 aa, and to Erwinia amylovora fructokinase ScrK SWALL:Q9F4A1 (EMBL:AJ250722) (308 aa) fasta scores: E(): 1.6e-65, 60.06% id in 303 aa; Belongs to the carbohydrate kinase PfkB family. (311 aa)    
Predicted Functional Partners:
scrB
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
 0.998
fruA
Similar to Escherichia coli pts system, fructose-specific IIbc component FruA or PtsF or b2167 SWALL:PTFB_ECOLI (SWALL:P20966) (563 aa) fasta scores: E(): 1.4e-146, 75.13% id in 567 aa.
     
 0.960
pgi
Glucose-6-phosphate isomerase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucose-6-phosphate isomerase Pgi or b4025 or z5623 or ecs5008 SWALL:G6PI_ECOLI (SWALL:P11537) (549 aa) fasta scores: E(): 1.4e-193, 86.86% id in 548 aa.
  
 
 0.960
ECA1968
Putative glycosyl hydrolase; Similar to Yersinia pestis putative glucosidase ypo0848 or y3233 SWALL:Q8ZHP2 (EMBL:AJ414145) (792 aa) fasta scores: E(): 0, 76.27% id in 784 aa, and to Bacillus thermoamyloliquefaciens alpha-glucosidase II SWALL:AGL2_BACTQ (SWALL:Q9F234) (787 aa) fasta scores: E(): 1.5e-66, 27.93% id in 784 aa; Belongs to the glycosyl hydrolase 31 family.
 
 
 0.955
manX
PTS system, mannose-specific IIab component; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri PTS system, mannose-specific iiab component ManX or PtsL or GptB or b1817 or c2223 or z2860 or ecs2527 or sf1411 SWALL:PTNA_ECOLI (SWALL:P08186) (322 aa) fasta scores: E(): 5.5e-80, 74.84% id in 322 aa.
  
 
 0.955
mtlD
Similar to Escherichia coli mannitol-1-phosphate 5-dehydrogenase MtlD or b3600 SWALL:MTLD_ECOLI (SWALL:P09424) (382 aa) fasta scores: E(): 5.7e-108, 77.48% id in 382 aa.
    
 0.952
xylA
Putative D-xylose isomerase; Similar to Escherichia coli xylose isomerase XylA SWALL:XYLA_ECOLI (SWALL:P00944) (440 aa) fasta scores: E(): 1.5e-155, 82.42% id in 438 aa.
    
 0.952
ECA2352
Putative 6-phosphofructokinase isozyme II; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
  
 0.951
pfkA
6-phosphofructokinase isozyme I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 0.951
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
  
 
 0.950
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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