STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0369Similar to Rhizobium meliloti putative amino acid decarboxylase, pyridoxal-dependent protein rb1241 SWALL:Q92U95 (EMBL:AL603646) (473 aa) fasta scores: E(): 3.5e-54, 42.5% id in 440 aa, and to Polyangium cellulosum aromatic amino acid decarboxylase Ddc SWALL:Q9L402 (EMBL:AJ270937) (512 aa) fasta scores: E(): 1.4e-17, 22.95% id in 453 aa. (450 aa)    
Predicted Functional Partners:
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
    
 0.959
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 
 0.943
putA
Bifunctional PutA protein [includes: proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
     
 0.943
thrA
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase I [includes: aspartokinase I; homoserine dehydrogenase I] thra or thra1 or thra2 or b0002 SWALL:AK1H_ECOLI (SWALL:P00561) (820 aa) fasta scores: E(): 0, 82.41% id in 819 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
     
 0.738
metL
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase II MetL or MetM or b3940 SWALL:AK2H_ECOLI (SWALL:P00562) (809 aa) fasta scores: E(): 0, 83.12% id in 800 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
     
 0.738
aspA1
Aspartate ammonia-lyase; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri aspartate ammonia-lyase AspA or b4139 or c5222 or sf4293 SWALL:ASPA_ECOLI (SWALL:P04422) (478 aa) fasta scores: E(): 7.8e-167, 88.05% id in 477 aa. Also similar to ECA0621 (91.195% id. in 477 aa overlap).
     
 0.674
ECA0370
Putative membrane protein; Similar to Pseudomonas aeruginosa hypothetical protein Pa1352 pa1352 SWALL:Q9I3Z2 (EMBL:AE004564) (403 aa) fasta scores: E(): 8.6e-83, 60.45% id in 397 aa, and to Escherichia coli hypothetical protein YgaY SWALL:YGAY_ECOLI (SWALL:P76628) (394 aa) fasta scores: E(): 1.5e-55, 41.17% id in 391 aa. Note that redicted start site of this feature is around 23 AA upstream of that predicted for its ortholgues.
       0.668
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
    
 0.661
asnB
Similar to Escherichia coli asparagine synthetase B [glutamine-hydrolyzing] AsnB or b0674 SWALL:ASNB_ECOLI (SWALL:P22106) (553 aa) fasta scores: E(): 9.7e-211, 91.68% id in 553 aa.
     
 0.660
gcvP
Putative glycine cleavage system P protein (glycine dehydrogenase [decarboxylating]); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.657
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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