STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0372Conserved hypothetical protein; Similar to Escherichia coli, and Shigella flexneri hypothetical protein YhbP SWALL:AAN44662 (EMBL:U18997) (147 aa) fasta scores: E(): 2.2e-29, 54.54% id in 143 aa; Belongs to the UPF0306 family. (164 aa)    
Predicted Functional Partners:
ECA0371
Putative transcriptional regulator; Similar to Pseudomonas putida conserved hypothetical protein pp0502 SWALL:AAN66130 (EMBL:AE016775) (147 aa) fasta scores: E(): 8e-26, 55.14% id in 136 aa. Note that there are no significant database matches to enterobacterial species.
       0.762
ECA0373
Similar to Salmonella typhi hypothetical protein sty3451 SWALL:Q8Z3I6 (EMBL:AL627278) (211 aa) fasta scores: E(): 2.2e-41, 55.76% id in 208 aa, and to Escherichia coli O157:H7 hypothetical protein YraR SWALL:Q8XAA0 (EMBL:AE005544) (226 aa) fasta scores: E(): 2.7e-41, 54.8% id in 208 aa.
  
    0.703
ECA2203
Similar to Yersinia pestis putative exported protein ypo2305 or y2136 SWALL:Q8ZE77 (EMBL:AJ414151) (317 aa) fasta scores: E(): 2.4e-78, 69.9% id in 319 aa, and to Shigella flexneri orf, conserved hypothetical protein sf1625 SWALL:AAN43208 (EMBL:AE015183) (314 aa) fasta scores: E(): 8.2e-74, 67.82% id in 317 aa.
  
     0.690
mukB
Cell division protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.
  
     0.651
pgpB
Phosphatidylglycerophosphatase B; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri phosphatidylglycerophosphatase B PgpB or b1278 or z2529 or ecs1851 or sf1282 SWALL:PGPB_ECOLI (SWALL:P18201) (254 aa) fasta scores: E(): 6.1e-68, 61.75% id in 251 aa.
  
     0.640
ECA0637
Similar to Escherichia coli hypothetical protein YqjK SWALL:YQJK_ECOLI (SWALL:Q47710) (99 aa) fasta scores: E(): 1.5e-17, 47.36% id in 95 aa, and to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein YqjK SWALL:Q8XGR1 (EMBL:AE008848) (99 aa) fasta scores: E(): 4.6e-17, 45.26% id in 95 aa.
  
     0.555
holE
DNA polymerase III, theta subunit; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri DNA polymerase III, theta subunit HolE or b1842 or c2252 or z2891 or ecs2552 or sf1852.1 SWALL:HOLE_ECOLI (SWALL:P28689) (76 aa) fasta scores: E(): 8.7e-18, 67.1% id in 76 aa.
  
     0.542
aaeB
Putative membrane protein; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
  
     0.536
tsx
Nucleoside-specific channel-forming protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri nucleoside-specific channel-forming protein Tsx precursor Tsx or NupA or b0411 or z0512 or ecs0464 or sf0348 SWALL:TSX_ECOLI (SWALL:P22786) (294 aa) fasta scores: E(): 3.1e-92, 73.46% id in 294 aa.
  
     0.528
ECA2883
Similar to Yersinia pestis hypothetical protein Ypo1864 SWALL:Q8ZF54 (EMBL:AJ414150) (74 aa) fasta scores: E(): 2.3e-16, 67.56% id in 74 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yecf or stm1949 or sty2157 SWALL:Q8XEK4 (EMBL:AE008786) (74 aa) fasta scores: E(): 7.4e-16, 62.16% id in 74 aa.
  
     0.526
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.