Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA0373Similar to Salmonella typhi hypothetical protein sty3451 SWALL:Q8Z3I6 (EMBL:AL627278) (211 aa) fasta scores: E(): 2.2e-41, 55.76% id in 208 aa, and to Escherichia coli O157:H7 hypothetical protein YraR SWALL:Q8XAA0 (EMBL:AE005544) (226 aa) fasta scores: E(): 2.7e-41, 54.8% id in 208 aa. (217 aa)    
Predicted Functional Partners:
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 0.992
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 0.744
nuoF
NADH-quinone oxidoreductase chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
   
 0.737
ECA0372
Conserved hypothetical protein; Similar to Escherichia coli, and Shigella flexneri hypothetical protein YhbP SWALL:AAN44662 (EMBL:U18997) (147 aa) fasta scores: E(): 2.2e-29, 54.54% id in 143 aa; Belongs to the UPF0306 family.
       0.706
nuoG
NADH-quinone oxidoreductase chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
   
 0.685
nuoE
NADH-quinone oxidoreductase chain E; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri NADH-quinone oxidoreductase chain E NuoE or b2285 or c2826 or sf2361 SWALL:NUOE_ECOLI (SWALL:P33601) (166 aa) fasta scores: E(): 2.7e-53, 84.27% id in 159 aa.
   
 0.677
nuoB
NADH-quinone oxidoreductase chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
 0.676
ECA0371
Putative transcriptional regulator; Similar to Pseudomonas putida conserved hypothetical protein pp0502 SWALL:AAN66130 (EMBL:AE016775) (147 aa) fasta scores: E(): 8e-26, 55.14% id in 136 aa. Note that there are no significant database matches to enterobacterial species.
       0.669
ECA2173
Conserved hypothetical protein; Similar to Xylella fastidiosa outer membrane protein xf1739 SWALL:Q9PCN9 (EMBL:AE003997) (385 aa) fasta scores: E(): 1.2e-61, 43.09% id in 355 aa, and to Xanthomonas axonopodis hypothetical protein Xac0250 SWALL:Q8PQS2 (EMBL:AE011649) (351 aa) fasta scores: E(): 1.5e-45, 38.16% id in 338 aa.
 
    0.618
ECA0370
Putative membrane protein; Similar to Pseudomonas aeruginosa hypothetical protein Pa1352 pa1352 SWALL:Q9I3Z2 (EMBL:AE004564) (403 aa) fasta scores: E(): 8.6e-83, 60.45% id in 397 aa, and to Escherichia coli hypothetical protein YgaY SWALL:YGAY_ECOLI (SWALL:P76628) (394 aa) fasta scores: E(): 1.5e-55, 41.17% id in 391 aa. Note that redicted start site of this feature is around 23 AA upstream of that predicted for its ortholgues.
 
     0.525
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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