STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdGAnaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (154 aa)    
Predicted Functional Partners:
nrdD
Similar to Escherichia coli anaerobic ribonucleoside-triphosphate reductase NrdD or b4238 SWALL:NRDD_ECOLI (SWALL:P28903) (712 aa) fasta scores: E(): 0, 85.97% id in 713 aa.
 
 
 0.994
queF
Putative GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
  
  
 0.798
ECA3553
Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri putative 6-pyruvoyl tetrahydrobiopterin synthase YgcM or b2765 or z4075 or ecs3620 or sf2781 SWALL:PTPS_ECOLI (SWALL:Q46903) (121 aa) fasta scores: E(): 8.1e-44, 86.66% id in 120 aa.
  
  
 0.727
adhE
Aldehyde-alcohol dehydrogenase; Similar to Escherichia coli, and Escherichia coli O157:H7 aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase, acetaldehyde dehydrogenase, and pyruvate-formate-lyase deactivase AdhE or Ana or b1241 or z2016 or ecs1741 SWALL:ADHE_ECOLI (SWALL:P17547) (890 aa) fasta scores: E(): 0, 89.1% id in 890 aa; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
   
 0.725
queC
Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)); Belongs to the QueC family.
  
  
 0.659
focA
Probable formate transporter; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 probable formate transporter 1 FocA or FocA_2 or b0904 or c1042 or z1250 or ecs0987 SWALL:FOCA_ECOLI (SWALL:P21501) (285 aa) fasta scores: E(): 8.3e-94, 80.7% id in 285 aa.
  
   
 0.633
nrdA
Ribonucleoside-diphosphate reductase 1 alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.615
nrdB
Similar to Escherichia coli, and Escherichia coli O157:H7 ribonucleoside-diphosphate reductase 1 beta chain NrdB or FtsB or b2235 or z3491 or ecs3118 SWALL:RIR2_ECOLI (SWALL:P00453) (375 aa) fasta scores: E(): 3.2e-139, 90.13% id in 375 aa.
     
 0.610
hypC
Hydrogenase isoenzymes formation protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hydrogenase isoenzymes formation protein HypC or b2728 or c3288 or z4037 or ecs3584 or sf2745 SWALL:HYPC_ECOLI (SWALL:P24191) (90 aa) fasta scores: E(): 5.9e-22, 64.83% id in 91 aa.
   
  
 0.546
grcA
Conserved hypothetical protein; Acts as a radical domain for damaged PFL and possibly other radical proteins.
  
     0.522
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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