Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECA0380Putative endoribonuclease; Similar to Salmonella typhimurium, and Salmonella typhi YjgF SWALL:Q9X445 (EMBL:AF095578) (128 aa) fasta scores: E(): 1.5e-36, 82.81% id in 128 aa, and to Yersinia pestis hypothetical protein Ypo3590 SWALL:Q8ZB37 (EMBL:AJ414157) (128 aa) fasta scores: E(): 5.4e-37, 83.59% id in 128 aa. (128 aa)    
Predicted Functional Partners:
pyrI
Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
  
    0.716
pyrB
Aspartate carbamoyltransferase catalytic subunit; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri aspartate carbamoyltransferase catalytic chain PyrB or b4245 or c5345 or z5856 or ecs5222 or sf4245 SWALL:PYRB_ECOLI (SWALL:P00479) (310 aa) fasta scores: E(): 7.7e-100, 85.43% id in 309 aa; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
    0.698
tdcB
Putative threonine dehydratase catabolic; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri threonine dehydratase catabolic TdcB or b3117 or c3875 or z4469 or ecs3997 or sf3157 SWALL:THD2_ECOLI (SWALL:P05792) (329 aa) fasta scores: E(): 9.6e-33, 38.14% id in 312 aa, and to Thermotoga maritima threonine dehydratase catabolic tm0356 SWALL:Q9WYJ1 (EMBL:AE001716) (401 aa) fasta scores: E(): 6.1e-41, 41.32% id in 317 aa.
 
 
 0.659
pheA
Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri P-protein [includes: chorismate mutase and prephenate dehydratase] PheA or b2599 or z3891 or ecs3462 or sf2659 SWALL:PHEA_ECOLI (SWALL:P07022) (386 aa) fasta scores: E(): 1e-115, 76.17% id in 382 aa.
  
 
 0.609
ECA1334
Similar to Escherichia coli putative esterase/lipase ybff or b0686 SWALL:YBFF_ECOLI (SWALL:P75736) (254 aa) fasta scores: E(): 5.2e-69, 67.58% id in 253 aa.
  
 
 0.605
tyrA
Similar to Escherichia coli T-protein [includes: chorismate mutase and prephenate dehydrogenase] TyrA or b2600 SWALL:TYRA_ECOLI (SWALL:P07023) (373 aa) fasta scores: E(): 1.6e-123, 87.13% id in 373 aa.
  
 
 0.597
ECA2040
Catabolic threonine dehydratase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri threonine dehydratase catabolic TdcB or b3117 or c3875 or z4469 or ecs3997 or sf3157 SWALL:THD2_ECOLI (SWALL:P05792) (329 aa) fasta scores: E(): 1.8e-38, 39.44% id in 322 aa, and to Pseudomonas aeruginosa probable serine/threonine dehydratase, degradative pa2683 SWALL:Q9I0F5 (EMBL:AE004696) (320 aa) fasta scores: E(): 4.2e-90, 74.13% id in 317 aa.
 
 
 0.561
ECA2376
Putative endoribonuclease; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein yoab or b1809 or c2213 or sf1419 SWALL:YOAB_ECOLI (SWALL:P76258) (114 aa) fasta scores: E(): 6.4e-31, 73.68% id in 114 aa, and to Yersinia pestis hypothetical protein ypo2070 or y2240 SWALL:Q8ZET3 (EMBL:AJ414151) (114 aa) fasta scores: E(): 1.4e-30, 71.93% id in 114 aa.
 
  
 0.534
ECA1767
Isochorismatase family protein; Similar to Lactococcus lactis hypothetical protein yvea or ll2054 SWALL:Q9CDZ6 (EMBL:AE006436) (176 aa) fasta scores: E(): 5.4e-12, 33.53% id in 167 aa, and to Clostridium acetobutylicum amidase from nicotinamidase family cac3465 SWALL:Q97DL0 (EMBL:AE007844) (178 aa) fasta scores: E(): 1.5e-09, 30.23% id in 172 aa.
  
 
 0.520
ilvA
Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
 
 
 0.507
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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