STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0405Putative permease; Similar to Salmonella typhimurium putative permease YjgP SWALL:Q8ZK27 (EMBL:AE008910) (366 aa) fasta scores: E(): 1.1e-107, 73.33% id in 360 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YjgP SWALL:YJGP_ECOLI (SWALL:P39340) (366 aa) fasta scores: E(): 1.3e-106, 73.46% id in 358 aa. YjgP belongs to a family of predicted permeases but there is no experimental evidence of this. (371 aa)    
Predicted Functional Partners:
ECA0406
Putative permease; Similar to Escherichia coli, and Escherichia coli O6 hypothetical protein YjgQ SWALL:YJGQ_ECOLI (SWALL:P39341) (360 aa) fasta scores: E(): 2.6e-108, 77.24% id in 356 aa, and to Salmonella typhimurium putative permease YjgQ SWALL:Q8ZK26 (EMBL:AE008910) (360 aa) fasta scores: E(): 2.6e-109, 78.37% id in 356 aa.YjgQ belongs to a family of predicted permeases but there is no experimental evidence of this.
 
0.999
ECA0289
ABC transporter, ATP-binding component; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri probable ABC transporter ATP-binding protein YhbG SWALL:AAN44707 (EMBL:D12938) (241 aa) fasta scores: E(): 2.5e-76, 90.87% id in 241 aa, and to Salmonella typhimurium, and Salmonella typhi putative ABC superfamily Yhbg SWALL:Q8XFR6 (EMBL:AE008852) (241 aa) fasta scores: E(): 1.1e-75, 90.04% id in 241 aa.
 
 
 0.987
lptC
Putative exported protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
 
 
 0.949
imp
Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
  
 0.843
ECA3269
HlyD family secretion protein; Similar to Rhizobium leguminosarum PrsE protein prsE SWALL:O05694 (EMBL:Y12758) (435 aa) fasta scores: E(): 4.6e-27, 29.72% id in 434 aa, and to Pseudomonas putida HlyD family secretion protein pp0166 SWALL:AAN65799 (EMBL:AE016774) (458 aa) fasta scores: E(): 1.9e-103, 65.19% id in 454 aa.
  
 
 0.765
ecfK
Putative surface antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
 
   
 0.670
holC
Similar to Escherichia coli DNA polymerase III, chi subunit HolC or b4259 SWALL:HOLC_ECOLI (SWALL:P28905) (147 aa) fasta scores: E(): 1.8e-40, 72.41% id in 145 aa.
 
     0.601
tolQ
TolQ protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
  
     0.601
lolB
Outer-membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
  
   
 0.594
lolA
Outer-membrane lipoproteins carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
 
     0.563
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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