Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ECA0425Putative outer membrane efflux protein; Similar to Vibrio cholerae hypothetical protein Vc1606 SWALL:Q9KRN0 (EMBL:AE004238) (476 aa) fasta scores: E(): 6e-69, 44.34% id in 451 aa, and to Shewanella oneidensis outer membrane efflux protein so4090 SWALL:AAN57064 (EMBL:AE015839) (473 aa) fasta scores: E(): 1.2e-68, 45.11% id in 450 aa. (473 aa)    
Predicted Functional Partners:
tolC
Similar to Escherichia coli outer membrane protein TolC precursor TolC or MtcB or MukA or RefI or b3035 SWALL:TOLC_ECOLI (SWALL:P02930) (495 aa) fasta scores: E(): 4.1e-124, 75.32% id in 466 aa, and to Erwinia chrysanthemi outer membrane protein TolC SWALL:Q93AG1 (EMBL:AF421372) (472 aa) fasta scores: E(): 2.3e-128, 77.89% id in 466 aa.
  
  
  0.976
ECA0424
Putative membrane protein; Similar to Vibrio cholerae hypothetical protein vc1607 SWALL:Q9KRM9 (EMBL:AE004238) (324 aa) fasta scores: E(): 1.5e-72, 62.03% id in 324 aa.
 
 0.976
ECA0422
Putative membrane protein; Similar to Vibrio vulnificus ABC-type multidrug transport system, permease component vv12691 SWALL:AAO11038 (EMBL:AE016806) (381 aa) fasta scores: E(): 1.2e-62, 45.26% id in 391 aa.
 
   
 0.950
ECA0423
Putative membrane protein; Similar to Vibrio cholerae hypothetical protein Vc1608 vc1608 SWALL:Q9KRM8 (EMBL:AE004238) (387 aa) fasta scores: E(): 3.2e-46, 38.08% id in 365 aa.
 
   
 0.945
macA
Similar to Escherichia coli macrolide-specific efflux protein MacA precursor MacA or b0878 SWALL:MACA_ECOLI (SWALL:P75830) (371 aa) fasta scores: E(): 8.9e-30, 37.17% id in 390 aa, and to Yersinia pestis putative HlyD family secretion protein ypo2999 or y1481 SWALL:AAM85052 (EMBL:AJ414154) (401 aa) fasta scores: E(): 3.8e-78, 64.69% id in 405 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.768
ECA2930
HlyD-family secretion protein; Similar to Pseudomonas putida RND efflux membrane fusion protein pp3301 SWALL:AAN68908 (EMBL:AE016786) (367 aa) fasta scores: E(): 2.8e-81, 70.1% id in 368 aa, and to Xylella fastidiosa component of multidrug efflux system xf2084 SWALL:Q9PBQ6 (EMBL:AE004023) (368 aa) fasta scores: E(): 3.9e-75, 63.95% id in 369 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.727
mdtA
Similar to Salmonella typhimurium putative HlyD family secretion protein stm2126 SWALL:Q8ZNQ3 (EMBL:AE008794) (413 aa) fasta scores: E(): 1.9e-84, 63.27% id in 403 aa, and to Salmonella typhi putative efflux system protein sty2339 SWALL:Q8Z5F8 (EMBL:AL627273) (413 aa) fasta scores: E(): 2.2e-84, 63.27% id in 403 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.727
ECA0801
Putative exported protein; Similar to Vibrio cholerae hypothetical protein vc0913 SWALL:Q9KTI9 (EMBL:AE004175) (352 aa) fasta scores: E(): 2.3e-10, 26.29% id in 232 aa, and to Shewanella oneidensis HlyD family secretion protein so3483 SWALL:AAN56476 (EMBL:AE015784) (369 aa) fasta scores: E(): 2.4e-09, 25.49% id in 251 aa. Note that there are no significant database matches to enterobacterial species; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.721
hasF
Similar to Pseudomonas fluorescens outer membrane protein HasF SWALL:Q9RHT0 (EMBL:AB023289) (442 aa) fasta scores: E(): 1.5e-85, 54.96% id in 433 aa, and to Erwinia chrysanthemi proteases secretion protein PrtF precursor prtF SWALL:PRTF_ERWCH (SWALL:P23598) (462 aa) fasta scores: E(): 2.1e-75, 48.82% id in 424 aa. Also similar to ECA2781 (48.956% identity in 431 aa overlap).
     
  0.666
prtF
Similar to Erwinia chrysanthemi proteases secretion protein PrtF precursor SWALL:PRTF_ERWCH (SWALL:P23598) (462 aa) fasta scores: E(): 3.6e-123, 73.25% id in 445 aa. Also similar to ECA1534 (48.956% in 431 aa overlap.
     
  0.666
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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