STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0425Putative outer membrane efflux protein; Similar to Vibrio cholerae hypothetical protein Vc1606 SWALL:Q9KRN0 (EMBL:AE004238) (476 aa) fasta scores: E(): 6e-69, 44.34% id in 451 aa, and to Shewanella oneidensis outer membrane efflux protein so4090 SWALL:AAN57064 (EMBL:AE015839) (473 aa) fasta scores: E(): 1.2e-68, 45.11% id in 450 aa. (473 aa)    
Predicted Functional Partners:
ECA0424
Putative membrane protein; Similar to Vibrio cholerae hypothetical protein vc1607 SWALL:Q9KRM9 (EMBL:AE004238) (324 aa) fasta scores: E(): 1.5e-72, 62.03% id in 324 aa.
 
 
 0.974
ECA0422
Putative membrane protein; Similar to Vibrio vulnificus ABC-type multidrug transport system, permease component vv12691 SWALL:AAO11038 (EMBL:AE016806) (381 aa) fasta scores: E(): 1.2e-62, 45.26% id in 391 aa.
 
   
 0.949
ECA0423
Putative membrane protein; Similar to Vibrio cholerae hypothetical protein Vc1608 vc1608 SWALL:Q9KRM8 (EMBL:AE004238) (387 aa) fasta scores: E(): 3.2e-46, 38.08% id in 365 aa.
 
   
 0.944
macB
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.749
cusB
Similar to Escherichia coli putative copper efflux system protein CusB precursor CusB or b0574 SWALL:CUSB_ECOLI (SWALL:P77239) (407 aa) fasta scores: E(): 8.2e-44, 37.94% id in 398 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.649
ECA1386
Putative exported protein; Similar to Escherichia coli hypothetical protein CusX precursor CusX or b0573 SWALL:CUSX_ECOLI (SWALL:P77214) (110 aa) fasta scores: E(): 1.5e-06, 35.13% id in 111 aa, and to Shigella flexneri orf, conserved hypothetical protein ylcc or sf0474 SWALL:AAN42127 (EMBL:AE015079) (110 aa) fasta scores: E(): 1.5e-06, 35.13% id in 111 aa.
  
 
 0.578
emrA
Similar to Erwinia chrysanthemi EmrA protein EmrA SWALL:Q93KB1 (EMBL:AJ410307) (391 aa) fasta scores: E(): 7.9e-104, 72.63% id in 391 aa, and to Escherichia coli multidrug resistance protein A EmrA or b2685 SWALL:EMRA_ECOLI (SWALL:P27303) (390 aa) fasta scores: E(): 5.7e-94, 68.28% id in 391 aa.
  
 
 0.526
ECA1096
Similar to Pseudomonas putida protein secretion ABC efflux system, membrane fusion protein pp0803 SWALL:AAN66428 (EMBL:AE016777) (394 aa) fasta scores: E(): 9.1e-67, 54.23% id in 378 aa, and to Escherichia coli O157:H7 putative membrane spanning export protein z0635 or ecs0544 SWALL:Q8XD11 (EMBL:AE005229) (391 aa) fasta scores: E(): 2.9e-66, 54.3% id in 372 aa.
  
 
 0.494
hasE
HlyD family secretion protein; Similar to Pseudomonas fluorescens membrane fusion protein HasE SWALL:Q9RHT1 (EMBL:AB023289) (443 aa) fasta scores: E(): 2.5e-67, 52.28% id in 438 aa, and to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 3.8e-62, 46.03% id in 441 aa. Also similar to ECA2782 (47.529% identity in 425 aa overlap).
  
 
 0.494
prtE
Similar to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 9.7e-110, 72.33% id in 441 aa. Also similar to ECA1535 (47.529% in 425 aa overlap.
  
 
 0.494
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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