STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
zapAConserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (109 aa)    
Predicted Functional Partners:
ihfA
Integration host factor alpha-subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
  
    0.800
zapB
Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
 
 
 0.726
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.693
ECA0460
Similar to Yersinia pestis hypothetical protein ypo0911 SWALL:Y911_YERPE (SWALL:Q8ZHI2) (192 aa) fasta scores: E(): 1.2e-49, 70.76% id in 195 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YgfB SWALL:YGFB_ECOLI (SWALL:P25533) (192 aa) fasta scores: E(): 4.4e-49, 70.25% id in 195 aa; Belongs to the UPF0149 family.
  
  
 0.686
lpp
Major outer membrane lipoprotein; A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
  
    0.673
mreD
Rod shape-determining protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
  
   
 0.670
smpA
Putative outer membrane lipopotein (small protein A); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
    0.664
cvpA
Similar to Escherichia coli colicin V production protein CvpA or DedE or b2313 SWALL:CVPA_ECOLI (SWALL:P08550) (162 aa) fasta scores: E(): 7.5e-53, 81.98% id in 161 aa.
 
  
 0.663
ECA0462
Similar to Oryctolagus cuniculus 5-formyltetrahydrofolate cyclo-ligase MthfS SWALL:FTHC_RABIT (SWALL:P80405) (201 aa) fasta scores: E(): 2.9e-11, 28.35% id in 201 aa, and to Yersinia pestis putative 5-formyltetrahydrofolate cyclo-ligase-family protein ypo0913 or y3300 SWALL:Q8ZHI0 (EMBL:AJ414145) (198 aa) fasta scores: E(): 1.2e-51, 67.87% id in 193 aa.
     
 0.651
pepP
Proline aminopeptidase II; Similar to Escherichia coli xaa-pro aminopeptidase PepP or b2908 SWALL:AMPP_ECOLI (SWALL:P15034) (440 aa) fasta scores: E(): 2.8e-138, 77.67% id in 430 aa; Belongs to the peptidase M24B family.
 
   
 0.612
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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