Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
smpPutative membrane protein; Similar to Escherichia coli, and Shigella flexneri protein Smp precursor Smp or b4387 or sf4419 SWALL:SMP_ECOLI (SWALL:P18838) (214 aa) fasta scores: E(): 3.9e-52, 65.72% id in 213 aa. (231 aa)    
Predicted Functional Partners:
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
  
  
  0.838
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
  
  
  0.800
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
  
  
  0.794
ECA2468
Putative exported protein; Similar to Salmonella typhimurium putative outer membrane protein ycfr or stm1214 SWALL:Q8ZQ03 (EMBL:AE008753) (85 aa) fasta scores: E(): 2.6e-06, 48.23% id in 85 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein ybij precursor ybij or b0802 or c0886 or sf0752 SWALL:YBIJ_ECOLI (SWALL:P41038) (86 aa) fasta scores: E(): 1.3e-05, 52.32% id in 86 aa.
  
     0.772
ECA0034
Putative exported protein; Similar to Yersinia pestis possible exported protein ypo0033 SWALL:Q8ZJQ9 (EMBL:AJ414141) (569 aa) fasta scores: E(): 1.9e-128, 55.37% id in 558 aa, and to Escherichia coli O6 hypothetical protein YicH SWALL:AAN82916 (EMBL:AE016769) (577 aa) fasta scores: E(): 5.3e-123, 48.92% id in 558 aa.
  
     0.771
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.771
lpoB
Putative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family.
  
     0.770
ftsN
Cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
     0.770
helD
Helicase IV; Similar to Escherichia coli helicase IV HelD or b0962 SWALL:HELD_ECOLI (SWALL:P15038) (684 aa) fasta scores: E(): 1.6e-197, 69.29% id in 684 aa.
  
    0.769
rof
Modulator of rho-dependent transcription termination; Similar to Escherichia coli, and Shigella flexneri Rof protein or b0189 or sf0179 SWALL:ROF_ECOLI (SWALL:P52098) (84 aa) fasta scores: E(): 3.4e-22, 70.23% id in 84 aa, and to Salmonella typhimurium modulator of rho-dependent transcription termination Rof or stm0237 SWALL:Q8ZRN4 (EMBL:AE008706) (86 aa) fasta scores: E(): 2.9e-20, 66.27% id in 86 aa.
  
     0.766
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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