STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0472Putative TatD-family deoxyribonuclease; Similar to Yersinia pestis putative metalloenzyme ypo0434 SWALL:Q8ZIQ6 (EMBL:AJ414142) (262 aa) fasta scores: E(): 1.3e-62, 64.2% id in 257 aa, and to Escherichia coli putative deoxyribonuclease YjjV SWALL:YJJV_ECOLI (SWALL:P39408) (259 aa) fasta scores: E(): 1.8e-61, 62.45% id in 253 aa. (265 aa)    
Predicted Functional Partners:
ECA0471
Similar to Xanthomonas axonopodis hypothetical protein xac4007 SWALL:Q8PFH4 (EMBL:AE012049) (69 aa) fasta scores: E(): 6.4e-07, 47.36% id in 57 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri protein YjbJ SWALL:AAN45582 (EMBL:U00006) (71 aa) fasta scores: E(): 0.00014, 37.93% id in 58 aa.
       0.548
ECA0473
Similar to Yersinia pestis putative Na+ dependent nucleoside transporter-family protein ypo0435 SWALL:Q8ZIQ5 (EMBL:AJ414142) (423 aa) fasta scores: E(): 9.9e-133, 84.39% id in 423 aa; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
 
     0.508
lepA
GTP-binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
 
    0.499
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
  
 0.446
gcp
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
     0.445
obg
Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
 
   
 0.439
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
   0.436
tpiA-2
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
   
 0.423
ECA0470
Putative membrane protein; Similar to Escherichia coli O157:H7 hypothetical protein Z5978 SWALL:Q8X479 (EMBL:AE005669) (59 aa) fasta scores: E(): 3.4e-16, 98.11% id in 53 aa, and to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein stm4562 or sty4912 SWALL:Q8XEW6 (EMBL:AE008914) (59 aa) fasta scores: E(): 4e-16, 96.22% id in 53 aa.
       0.407
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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