STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0489Similar to Escherichia coli 2-hydroxy-3-oxopropionate reductase GlxR or GlxB1 or b0509 SWALL:GLXR_ECOLI (SWALL:P77161) (292 aa) fasta scores: E(): 4.9e-13, 26.16% id in 279 aa, and to Pseudomonas aeruginosa probable 3-hydroxyisobutyrate dehydrogenase pa3312 SWALL:Q9HYT2 (EMBL:AE004753) (296 aa) fasta scores: E(): 3.4e-17, 31.09% id in 283 aa. (297 aa)    
Predicted Functional Partners:
phnG
Putative phosphonate metabolism protein; Similar to Escherichia coli PhnG protein PhnG or b4101 SWALL:PHNG_ECOLI (SWALL:P16685) (150 aa) fasta scores: E(): 8.5e-27, 50.68% id in 146 aa.
       0.777
ltnD
Putative oxidoreductase; Catalyzes oxidation of L-threonate to 2-oxo-tetronate. Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
  
     0.771
phnH
Putative phosphonate metabolism protein; Similar to Escherichia coli PhnH protein phnH SWALL:PHNH_ECOLI (SWALL:P16686) (194 aa) fasta scores: E(): 5.7e-26, 41.57% id in 190 aa.
       0.737
phnI
Putative phosphonate metabolism protein; Similar to Yersinia pestis PhnI protein SWALL:Q8ZBF7 (EMBL:AJ414157) (392 aa) fasta scores: E(): 3.9e-100, 72.65% id in 362 aa, and to Escherichia coli PhnI SWALL:PHNI_ECOLI (SWALL:P16687) (354 aa) fasta scores: E(): 8.5e-95, 69.46% id in 357 aa.
       0.737
phnJ
Putative phosphonate metabolism protein; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family.
       0.737
phnK
Similar to Escherichia coli phosphonates transport ATP-binding protein PhnK SWALL:PHNK_ECOLI (SWALL:P16678) (252 aa) fasta scores: E(): 6.3e-69, 76.77% id in 254 aa.
       0.737
garL
2-dehydro-3-deoxyglucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
 
 
  0.700
phnL
Similar to Escherichia coli phosphonates transport ATP-binding protein phnl phnl or b4096 SWALL:PHNL_ECOLI (SWALL:P16679) (226 aa) fasta scores: E(): 2.6e-55, 65.77% id in 225 aa.
       0.670
phnM
Putative phosphonate metabolism protein; Similar to Escherichia coli PhnM SWALL:PHNM_ECOLI (SWALL:P16689) (378 aa) fasta scores: E(): 5.3e-94, 62.96% id in 378 aa.
       0.670
phnN
Putative phosphonate metabolism protein; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
       0.670
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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