Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilTPutative Type IV pilus protein; Similar to Salmonella typhi, and Salmonella dublin PilT protein PilT or sty4548 SWALL:Q9ZIU8 (EMBL:AF000001) (158 aa) fasta scores: E(): 2.3e-28, 55.07% id in 138 aa, and to Escherichia coli, and Salmonella typhimurium PilT protein PilT SWALL:O07378 (EMBL:AB021078) (186 aa) fasta scores: E(): 7.9e-28, 45.88% id in 170 aa. (172 aa)    
Predicted Functional Partners:
pilR
Putative Type IV pilus protein; Similar to Escherichia coli, and Salmonella typhimurium integral membrane protein PilR SWALL:O07376 (EMBL:AB021078) (365 aa) fasta scores: E(): 7.1e-24, 29.68% id in 347 aa, and to Yersinia pseudotuberculosis integral membrane protein PilR SWALL:Q8KR26 (EMBL:AY047316) (369 aa) fasta scores: E(): 5.5e-23, 30.2% id in 341 aa.
 
     0.854
pilS
Similar to Yersinia pseudotuberculosis type IV prepilin PilS SWALL:Q8KR25 (EMBL:AY047316) (195 aa) fasta scores: E(): 1.2e-05, 31.84% id in 179 aa, and to Escherichia coli type IV prepilin PilS SWALL:O88170 (EMBL:AB007463) (204 aa) fasta scores: E(): 0.013, 29.05% id in 179 aa.
       0.773
pilU
Similar to Shigella sonnei prepilin peptidase PilU SWALL:Q9R2J4 (EMBL:AB021078) (218 aa) fasta scores: E(): 0.029, 26.33% id in 224 aa, and to Salmonella typhimurium prepilin peptidase pPilU SWALL:O07379 (EMBL:AB027308) (218 aa) fasta scores: E(): 0.025, 26.33% id in 224 aa.
       0.773
pilV
Putative Type IV pilus prepilin protein; Similar to Escherichia coli PilV protein PilV SWALL:Q04905 (EMBL:X62169) (417 aa) fasta scores: E(): 8.8e-12, 32.47% id in 428 aa, and to Salmonella typhi PilV or sty4550 or t4250 SWALL:O51801 (EMBL:AF000001) (435 aa) fasta scores: E(): 7.5e-13, 26.49% id in 453 aa.
       0.772
ECA0545
Alternative C-terminus for the PilV protein (fragment); Similar to the C-terminal region of Escherichia coli PilV SWALL:AAL18837 (EMBL:AY258503) (454 aa) fasta scores: E(): 6.6e-10, 36.3% id in 157 aa, and to Salmonella typhi probable variable tail fibre protein sty3691 SWALL:Q8Z343 (EMBL:AL627279) (504 aa) fasta scores: E(): 1.5e-13, 39.58% id in 144 aa.
       0.741
hrcC
Type III secretion protein; Similar to Pectobacterium carotovorum subsp. carotovorum HrcC SWALL:Q93FZ1 (EMBL:AF302656) (689 aa) fasta scores: E(): 0, 95.78% id in 688 aa, and to Erwinia amylovora HrcC precursor SWALL:Q46625 (EMBL:U56662) (676 aa) fasta scores: E(): 1.3e-169, 68.65% id in 654 aa.
 
  
 0.739
pilN
Putative Type IV pilus protein; Similar to Escherichia coli, and Salmonella typhimurium lipoprotein PilN SWALL:O07372 (EMBL:AB021078) (560 aa) fasta scores: E(): 8.1e-61, 40.71% id in 560 aa.
 
  
 0.720
hrcT
Type III secretion protein; Similar to Erwinia amylovora HrcT SWALL:Q46648 (EMBL:L25828) (265 aa) fasta scores: E(): 2.4e-69, 66.92% id in 257 aa, and to Pantoea agglomerans HrcT protein HrcT SWALL:Q47858 (EMBL:X99768) (265 aa) fasta scores: E(): 4.5e-67, 62.3% id in 260 aa.
  
  
 0.602
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
  
 0.543
obg
Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
      
 0.530
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (12%) [HD]