STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
traFPutative plasmid transfer protein; Similar to Shigella sonnei TraF protein SWALL:Q9Z4A1 (EMBL:AB021078) (400 aa) fasta scores: E(): 2.9e-81, 55% id in 400 aa, and to Salmonella typhimurium TraF protein SWALL:Q9R2H5 (EMBL:AB027308) (400 aa) fasta scores: E(): 3.4e-81, 54.75% id in 400 aa, and to Escherichia fergusonii TraF SWALL:Q8KR61 (EMBL:AY046057) (401 aa) fasta scores: E(): 1e-61, 44.52% id in 402 aa. (400 aa)    
Predicted Functional Partners:
srfB
Putative virulence effector protein; Similar to Salmonella typhimurium SrfB or stm1594 SWALL:Q9KIJ9 (EMBL:AF231758) (993 aa) fasta scores: E(): 0, 57.47% id in 997 aa, and to Yersinia pestis putative virulence factor ypo2290 SWALL:Q8ZE92 (EMBL:AJ414151) (1023 aa) fasta scores: E(): 2.1e-214, 73.8% id in 1027 aa.
  
   
 0.755
ECA2357
Putative kinase; Similar to Brucella suis shikimate kinase Arok or br2029 SWALL:Q8FY59 (EMBL:AE014491) (200 aa) fasta scores: E(): 2.3, 20.78% id in 178 aa, and to the C-terminal region of Rhizobium loti glucokinase mlr3412 SWALL:Q98GB0 (EMBL:AP003001) (482 aa) fasta scores: E(): 1.5e-27, 45.71% id in 175 aa.
  
     0.662
srfA
Putative virulence effector protein; Similar to Salmonella typhimurium, and Salmonella typhi SrfA or sty1472 SWALL:Q9KIK0 (EMBL:AF231758) (399 aa) fasta scores: E(): 2.4e-16, 41.06% id in 431 aa, and to Yersinia pestis putative virulence factor y2121 SWALL:AAM85682 (EMBL:AE013815) (477 aa) fasta scores: E(): 4.2e-29, 51.02% id in 488 aa.
  
   
 0.623
ECA0550
Similar to Proteus vulgaris hypothetical protein orf267 SWALL:Q8KJV9 (EMBL:AP004237) (138 aa) fasta scores: E(): 6.8e-24, 57.46% id in 134 aa, and to Pseudomonas resinovorans hypothetical protein SWALL:Q8GHW2 (EMBL:AB088420) (169 aa) fasta scores: E(): 3.9e-05, 39.17% id in 97 aa.
       0.578
mtlR
Mannitol operon repressor; Similar to Escherichia coli, and Escherichia coli O6 mannitol operon repressor MtlR or b3601 or c4418 SWALL:MTLR_ECOLI (SWALL:P36563) (195 aa) fasta scores: E(): 2.6e-47, 74.15% id in 178 aa.
  
     0.572
ECA1841
Similar to Escherichia coli hypothetical protein ydiv or b1707 SWALL:YDIV_ECOLI (SWALL:P76204) (237 aa) fasta scores: E(): 3.5e-23, 36.17% id in 235 aa, and to Shigella flexneri orf, conserved hypothetical protein ydiv or sf1524 SWALL:AAN43114 (EMBL:AE015175) (237 aa) fasta scores: E(): 3.1e-22, 35.74% id in 235 aa.
  
     0.567
lpoA
Putative exported protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family.
  
   
 0.548
wecH
Putative membrane protein; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.
  
     0.547
dusB
Putative dihydrourdine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.
     
 0.547
rsd
Regulator of sigma D; Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
  
     0.545
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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