Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cutAPeriplasmic divalent cation tolerance protein; Involved in resistance toward heavy metals; Belongs to the CutA family. (111 aa)    
Predicted Functional Partners:
dsbD
Thiol:disulfide interchange protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
  
  
 0.900
ECA0617
Conserved hypothetical protein; Similar to Yersinia pestis putative TetR-family regulatory protein ypo0341 SWALL:Q8ZIZ3 (EMBL:AJ414142) (191 aa) fasta scores: E(): 4.5e-49, 68.58% id in 191 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri protein YjdC SWALL:AAN45707 (EMBL:Z36905) (191 aa) fasta scores: E(): 1.3e-48, 64.92% id in 191 aa.
 
   
 0.805
fxsA
Suppressor of F plamsid exlusion of phage T7; Similar to Escherichia coli FxsA protein FxsA or b4140 SWALL:FXSA_ECOLI (SWALL:P37147) (158 aa) fasta scores: E(): 1.3e-38, 68.35% id in 158 aa.
     
 0.490
dcuA
Anaerobic C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
       0.478
groS
10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
  
 0.473
cutC
Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family.
      
 0.450
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
     
 0.418
dsbC
Thiol:disulfide interchange protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
      
 0.404
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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