Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
aspA2Aspartate ammonia-lyase 2; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri aspartate ammonia-lyase AspA or b4139 or c5222 or sf4293 SWALL:ASPA_ECOLI (SWALL:P04422) (478 aa) fasta scores: E(): 3.2e-169, 89.09% id in 477 aa. Also similar to ECA0426 (91.195% id. in 477 aa overlap). (479 aa)    
Predicted Functional Partners:
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 
 0.984
ansA
Similar to Escherichia coli, and Escherichia coli O157:H7 L-asparaginase I AnsA or b1767 or z2801 or ecs2474 SWALL:ASG1_ECOLI (SWALL:P18840) (338 aa) fasta scores: E(): 7e-103, 81.12% id in 339 aa.
  
  
  0.944
ECA0132
L-asparaginase; Similar to Arabidopsis thaliana L-asparaginase at5g08100 or t22d6_40 SWALL:ASPG_ARATH (SWALL:P50287) (315 aa) fasta scores: E(): 7.9e-38, 44.22% id in 303 aa, and to Escherichia coli putative L-asparaginase precursor ybik or b0828 SWALL:ASGX_ECOLI (SWALL:P37595) (321 aa) fasta scores: E(): 3.2e-73, 65.39% id in 315 aa.
     
  0.936
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 
 0.912
purB
Adenylosuccinate lyase; Similar to Escherichia coli, and Escherichia coli O6 adenylosuccinate lyase PurB or b1131 or c1510 SWALL:PUR8_ECOLI (SWALL:P25739) (456 aa) fasta scores: E(): 1.8e-159, 88.81% id in 456 aa.
  
 0.910
fumA
Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.908
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.887
asnB
Similar to Escherichia coli asparagine synthetase B [glutamine-hydrolyzing] AsnB or b0674 SWALL:ASNB_ECOLI (SWALL:P22106) (553 aa) fasta scores: E(): 9.7e-211, 91.68% id in 553 aa.
     
 0.879
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
  0.879
pyrI
Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
     
  0.878
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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