STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zurZinc uptake regulation protein; Similar to Escherichia coli, and Shigella flexneri zinc uptake regulation protein Zur or b4046 or sf4159 SWALL:ZUR_ECOLI (SWALL:P32692) (171 aa) fasta scores: E(): 8.5e-46, 68.63% id in 169 aa; Belongs to the Fur family. (171 aa)    
Predicted Functional Partners:
znuC
High-affinity zinc uptake system ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
  
  
 0.706
ECA1759
Putative CoA binding protein; Similar to Yersinia pestis hypothetical protein ypo1443 or y2727 SWALL:AAM86279 (EMBL:AJ414148) (138 aa) fasta scores: E(): 1.5e-35, 75.18% id in 137 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein stm1078 or sty1101 SWALL:Q8XGM9 (EMBL:AE008747) (138 aa) fasta scores: E(): 1.8e-34, 72.99% id in 137 aa.
  
    0.566
ECA1117
Probable peroxidase; Similar to Yersinia pestis putative alkyl hydroperoxide reductase subunit C AhpC or ypo3194 or y0988 SWALL:AAM84569 (EMBL:AJ414155) (200 aa) fasta scores: E(): 2.6e-76, 91.5% id in 200 aa, and to Vibrio vulnificus peroxiredoxin vv10453 SWALL:AAO08975 (EMBL:AE016798) (202 aa) fasta scores: E(): 1.4e-61, 73.5% id in 200 aa.
  
  
 0.555
ahpC
Alkyl hydroperoxide reductase C22 protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
  
 0.555
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.554
ECA0633
Similar to Salmonella typhi hypothetical protein sty3416 SWALL:Q8Z3K9 (EMBL:AL627278) (233 aa) fasta scores: E(): 1.4e-65, 68.67% id in 233 aa, and to Escherichia coli hypothetical protein YhaK SWALL:YHAK_ECOLI (SWALL:P42624) (233 aa) fasta scores: E(): 2.8e-63, 67.38% id in 233 aa; Belongs to the pirin family.
       0.535
nadR
Similar to Salmonella typhimurium transcriptional regulator NadR SWALL:NADR_SALTY (SWALL:P24518) (410 aa) fasta scores: E(): 1.1e-140, 85.5% id in 407 aa, and to Escherichia coli transcriptional regulator NadR or NadI or b4390 SWALL:NADR_ECOLI (SWALL:P27278) (410 aa) fasta scores: E(): 2.2e-139, 83.9% id in 410 aa.
  
  
 0.527
znuA
Similar to Escherichia coli high-affinity zinc uptake system protein ZnuA precursor ZnuA or b1857 SWALL:ZNUA_ECOLI (SWALL:P39172) (310 aa) fasta scores: E(): 4.6e-47, 61.05% id in 321 aa.
  
  
 0.510
norV
Anaerobic nitric oxide reductase flavorubredoxin; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family.
  
  
 0.504
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
     
 0.491
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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