STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0642Similar to Yersinia pestis putative DedA-family membrane protein ypo0574 SWALL:Q8ZID1 (EMBL:AJ414143) (232 aa) fasta scores: E(): 1.2e-71, 77.29% id in 229 aa, and to Salmonella typhimurium putative DedA family, membrane protein stm3226 SWALL:Q8ZLX0 (EMBL:AE008848) (220 aa) fasta scores: E(): 2.8e-67, 76.27% id in 215 aa. (227 aa)    
Predicted Functional Partners:
mzrA
Putative exported protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
  
  
 0.810
ECA0640
Putative exported protein; Similar to Salmonella typhimurium, and Salmonella typhi putative periplasmic protein stm3228 or sty3408 SWALL:Q8XF23 (EMBL:AE008848) (122 aa) fasta scores: E(): 1.4e-12, 49.15% id in 118 aa, and to Escherichia coli protein YqjC SWALL:YQJC_ECOLI (SWALL:P42616) (122 aa) fasta scores: E(): 1.6e-12, 50.83% id in 120 aa.
     
 0.780
ECA0638
Putative membrane protein; Similar to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein stm3230 or sty3410 SWALL:Q8XFR8 (EMBL:AE008848) (132 aa) fasta scores: E(): 8.1e-30, 67.69% id in 130 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YqjE SWALL:YQJE_ECOLI (SWALL:P42618) (134 aa) fasta scores: E(): 1.3e-28, 64.39% id in 132 aa.
 
   
 0.522
mtfA
Conserved hypothetical protein; Involved in the regulation of ptsG expression by binding and inactivating Mlc.
  
  
 0.473
ECA0639
Similar to Yersinia pestis putative membrane protein ypo0570 SWALL:AAM87157 (EMBL:AJ414143) (101 aa) fasta scores: E(): 2.3e-22, 76.23% id in 101 aa, and to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein stm3229 or sty3409 SWALL:Q8XEQ1 (EMBL:AE008848) (101 aa) fasta scores: E(): 9.6e-21, 71.28% id in 101 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YqjD SWALL:YQJD_ECOLI (SWALL:P42617) (101 aa) fasta scores: E(): 2.2e-20, 69.3% id in 101 aa.
       0.449
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
     
 0.443
ECA0637
Similar to Escherichia coli hypothetical protein YqjK SWALL:YQJK_ECOLI (SWALL:Q47710) (99 aa) fasta scores: E(): 1.5e-17, 47.36% id in 95 aa, and to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein YqjK SWALL:Q8XGR1 (EMBL:AE008848) (99 aa) fasta scores: E(): 4.6e-17, 45.26% id in 95 aa.
       0.439
macB
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
    0.410
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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