STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sfsBSugar fermentation stimulation protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri sugar fermentation stimulation protein B SfsB or Nlp or sfs7 or b3188 or c3946 or z4551 or ecs4067 or sf3228 SWALL:SFSB_ECOLI (SWALL:P18837) (92 aa) fasta scores: E(): 5.7e-20, 70.88% id in 79 aa. Also similar to ECA0513 (71.233% id. in 73 aa overlap), and to ECA0966 (72.368% id. in 76 aa overlap), and to ECA3206 (76.119% id. in 67 aa overlap.). (87 aa)    
Predicted Functional Partners:
ECA0687
Putative DNA-binding protein; Similar to Yersinia pestis hypothetical protein ypo3514 SWALL:AAM84258 (EMBL:AJ414157) (133 aa) fasta scores: E(): 1.9e-17, 47.32% id in 112 aa and to bacteriophage D3112 transposase A SWALL:Q38013 (EMBL:X87627) (690 aa) fasta scores: E(): 0.00026, 33.69% id in 92 aa.
 
     0.764
ECA2203
Similar to Yersinia pestis putative exported protein ypo2305 or y2136 SWALL:Q8ZE77 (EMBL:AJ414151) (317 aa) fasta scores: E(): 2.4e-78, 69.9% id in 319 aa, and to Shigella flexneri orf, conserved hypothetical protein sf1625 SWALL:AAN43208 (EMBL:AE015183) (314 aa) fasta scores: E(): 8.2e-74, 67.82% id in 317 aa.
  
     0.733
ECA3700
Similar to Neisseria meningitidis hypothetical protein nma1871 or rth11 SWALL:Q9JRE4 (EMBL:AL162757) (203 aa) fasta scores: E(): 7e-29, 41% id in 200 aa, and to Shewanella oneidensis conserved hypothetical protein so0648 SWALL:AAN53726 (EMBL:AE015511) (208 aa) fasta scores: E(): 1.5e-21, 33.84% id in 195 aa.
 
    0.673
holE
DNA polymerase III, theta subunit; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri DNA polymerase III, theta subunit HolE or b1842 or c2252 or z2891 or ecs2552 or sf1852.1 SWALL:HOLE_ECOLI (SWALL:P28689) (76 aa) fasta scores: E(): 8.7e-18, 67.1% id in 76 aa.
  
     0.580
ECA2004
Putative lipoprotein; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein ynbe or b1382 or c1829 or sf1816 SWALL:YNBE_ECOLI (SWALL:P76075) (61 aa) fasta scores: E(): 2.7e-10, 73.21% id in 56 aa, and to Salmonella typhimurium, and Salmonella typhi putative outer membrane lipoprotein ynbe or stm1645 or sty1424 SWALL:Q8XEM6 (EMBL:AE008772) (63 aa) fasta scores: E(): 1.5e-09, 60.65% id in 61 aa.
  
     0.573
ECA2693
Similar to Yersinia pestis hypothetical protein Ypo3467 SWALL:Q8ZBE9 (EMBL:AJ414157) (147 aa) fasta scores: E(): 3.7e-20, 39.71% id in 141 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yhbp or stm3270 or sty3453 SWALL:Q8XEW3 (EMBL:AE008850) (147 aa) fasta scores: E(): 4.1e-14, 28.96% id in 145 aa.
  
     0.556
hha
Haemolysin expression modulating protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri haemolysin expression modulating protein Hha or b0460 or c0578 or z0573 or ecs0513 or sf0405 SWALL:HHA_ECOLI (SWALL:P23870) (72 aa) fasta scores: E(): 1.1e-20, 77.61% id in 67 aa.
  
     0.541
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
      
 0.530
emrR
Negative regulator of multidrug resistance; Similar to Erwinia chrysanthemi EmrR protein EmrR SWALL:Q93KB2 (EMBL:AJ410307) (170 aa) fasta scores: E(): 2.2e-50, 77.51% id in 169 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 transcriptional repressor MprA or EmrR or b2684 or c3237 or z3985 or ecs3546 SWALL:MPRA_ECOLI (SWALL:P24201) (176 aa) fasta scores: E(): 1.7e-45, 71.34% id in 171 aa.
  
     0.515
pagP
Putative antimicrobial peptide resistance and lipid A acylation protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.
  
     0.502
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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