STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dacDSimilar to Escherichia coli penicillin-binding protein 4 precursor [includes: d-alanyl-d- alanine carboxypeptidase; D-alanyl-D-alanine-endopeptidase] DacB or b3182 SWALL:PBP4_ECOLI (SWALL:P24228) (477 aa) fasta scores: E(): 2.2e-146, 76.31% id in 477 aa; deleted EC_number 3.4.99.-. (477 aa)    
Predicted Functional Partners:
dacA
D-alanine carboxypeptidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 penicillin-binding protein 5 precursor DacA or Pfv or b0632 or c0722 or z0777 or ecs0670 SWALL:DACA_ECOLI (SWALL:P04287) (403 aa) fasta scores: E(): 4.5e-125, 79.9% id in 403 aa; Belongs to the peptidase S11 family.
     
 0.911
dacC
Similar to Escherichia coli penicillin-binding protein 6 precursor DacC or b0839 SWALL:DACC_ECOLI (SWALL:P08506) (400 aa) fasta scores: E(): 3.5e-111, 71.6% id in 398 aa; Belongs to the peptidase S11 family.
     
 0.911
ompA
Outer-membrane protein A; Similar to Erwinia carotovora putative outer-membrane protein a precursor OmpA SWALL:Q9RM69 (EMBL:AJ249340) (367 aa) fasta scores: E(): 2.6e-120, 90.32% id in 372 aa, and to Serratia marcescens outer membrane protein a precursor OmpA SWALL:OMPA_SERMA (SWALL:P04845) (359 aa) fasta scores: E(): 4.8e-71, 75.61% id in 369 aa; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
 
     0.661
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
  
  
 0.636
ECA2546
Similar to Yersinia pestis putative exported protein ypo1407 or y2763 SWALL:AAM86315 (EMBL:AJ414148) (618 aa) fasta scores: E(): 1.4e-92, 60.48% id in 615 aa, and to Vibrio cholerae hypothetical protein Vc1268 SWALL:Q9KSI8 (EMBL:AE004206) (524 aa) fasta scores: E(): 7.1e-47, 36.56% id in 495 aa.
  
  
 0.629
ftsI
Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
     
 0.621
ECA0821
Putative exported protein; Similar to Salmonella typhimurium, and Salmonella typhi putative periplasmic protein YbiS or SWALL:Q8XFD8 (EMBL:AE008734) (306 aa) fasta scores: E(): 1.9e-74, 67.64% id in 306 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protein YbiS precursor SWALL:YBIS_ECOLI (SWALL:P75789) (306 aa) fasta scores: E(): 2.8e-74, 67.64% id in 306 aa.
  
  
 0.605
mrcB
Penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
     
 0.595
ECA2528
Similar to Yersinia pestis hypothetical protein ypo2038 or y2274 SWALL:AAM85834 (EMBL:AJ414151) (186 aa) fasta scores: E(): 2.8e-45, 67.22% id in 180 aa, and to Escherichia coli hypothetical protein ycdy or b1035 SWALL:YCDY_ECOLI (SWALL:P75915) (184 aa) fasta scores: E(): 1.1e-41, 60.42% id in 187 aa.
  
    0.587
ECA4348
Similar to Yersinia pestis putative membrane protein ypo3816a or y0414 SWALL:Q8ZAI5 (EMBL:AJ414159) (90 aa) fasta scores: E(): 1.2e-22, 71.59% id in 88 aa, and to Shigella flexneri orf, conserved hypothetical protein yhhl or sf3484 SWALL:AAN44943 (EMBL:AE015356) (90 aa) fasta scores: E(): 5.6e-22, 69.41% id in 85 aa.
  
     0.556
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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