Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dacDSimilar to Escherichia coli penicillin-binding protein 4 precursor [includes: d-alanyl-d- alanine carboxypeptidase; D-alanyl-D-alanine-endopeptidase] DacB or b3182 SWALL:PBP4_ECOLI (SWALL:P24228) (477 aa) fasta scores: E(): 2.2e-146, 76.31% id in 477 aa; deleted EC_number 3.4.99.-. (477 aa)    
Predicted Functional Partners:
ftsI
Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
     
 0.984
mrcB
Penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
     
 0.978
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
  
  
 0.977
mrcA
Similar to Escherichia coli penicillin-binding protein 1A MrcA or PonA or b3396 SWALL:PBPA_ECOLI (SWALL:P02918) (850 aa) fasta scores: E(): 0, 77.9% id in 851 aa.
  
  
 0.967
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
  
 0.964
dacA
D-alanine carboxypeptidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 penicillin-binding protein 5 precursor DacA or Pfv or b0632 or c0722 or z0777 or ecs0670 SWALL:DACA_ECOLI (SWALL:P04287) (403 aa) fasta scores: E(): 4.5e-125, 79.9% id in 403 aa; Belongs to the peptidase S11 family.
     
 0.953
dacC
Similar to Escherichia coli penicillin-binding protein 6 precursor DacC or b0839 SWALL:DACC_ECOLI (SWALL:P08506) (400 aa) fasta scores: E(): 3.5e-111, 71.6% id in 398 aa; Belongs to the peptidase S11 family.
     
 0.953
ECA0077
Putative exported protein; Similar to Pyrococcus abyssi related beta-lactamase precursor Pbp SWALL:Q9V2D6 (EMBL:AJ248283) (447 aa) fasta scores: E(): 2.5e-14, 22.94% id in 340 aa, and to Bacillus cereus alkaline D-peptidase adP SWALL:P94288 (EMBL:D86380) (388 aa) fasta scores: E(): 1.7e-10, 29.52% id in 254 aa.
    
 0.672
ompA
Outer-membrane protein A; Similar to Erwinia carotovora putative outer-membrane protein a precursor OmpA SWALL:Q9RM69 (EMBL:AJ249340) (367 aa) fasta scores: E(): 2.6e-120, 90.32% id in 372 aa, and to Serratia marcescens outer membrane protein a precursor OmpA SWALL:OMPA_SERMA (SWALL:P04845) (359 aa) fasta scores: E(): 4.8e-71, 75.61% id in 369 aa; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
 
     0.660
ECA2546
Similar to Yersinia pestis putative exported protein ypo1407 or y2763 SWALL:AAM86315 (EMBL:AJ414148) (618 aa) fasta scores: E(): 1.4e-92, 60.48% id in 615 aa, and to Vibrio cholerae hypothetical protein Vc1268 SWALL:Q9KSI8 (EMBL:AE004206) (524 aa) fasta scores: E(): 7.1e-47, 36.56% id in 495 aa.
  
  
 0.640
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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