| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA0696 | aroE | ECA0696 | ECA3995 | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.578 |
| ECA0696 | csrA | ECA0696 | ECA3366 | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Belongs to the CsrA/RsmA family. | 0.633 |
| ECA0696 | infA | ECA0696 | ECA2653 | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.493 |
| ECA0696 | nadD | ECA0696 | ECA1306 | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.752 |
| ECA0696 | pehA | ECA0696 | ECA1095 | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | Endo-polygalacturonase; Similar to Erwinia carotovora endo-polygalacturonase precursor PehA SWALL:PGL2_ERWCA (SWALL:P26509) (402 aa) fasta scores: E(): 1.4e-143, 97.76% id in 402 aa, and to Erwinia carotovora Peh precursor SWALL:Q9S5V7 (EMBL:AB022681) (402 aa) fasta scores: E(): 1.3e-140, 95.77% id in 402 aa; Belongs to the glycosyl hydrolase 28 family. | 0.502 |
| ECA0696 | rne | ECA0696 | ECA1789 | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.548 |
| ECA0696 | rrmJ | ECA0696 | ECA0697 | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | Ribosomal RNA large subunit methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.595 |
| ECA0696 | rsfS | ECA0696 | ECA1305 | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.617 |
| ECA0696 | rsmC | ECA0696 | ECA0735 | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | Ribosomal RNA small subunit methyltransferase C; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | 0.574 |
| ECA0696 | sun | ECA0696 | ECA4001 | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.717 |
| aroE | ECA0696 | ECA3995 | ECA0696 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | 0.578 |
| aroE | nadD | ECA3995 | ECA1306 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.706 |
| aroE | rsfS | ECA3995 | ECA1305 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.460 |
| aroE | sun | ECA3995 | ECA4001 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.649 |
| csrA | ECA0696 | ECA3366 | ECA0696 | Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Belongs to the CsrA/RsmA family. | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | 0.633 |
| csrA | rne | ECA3366 | ECA1789 | Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Belongs to the CsrA/RsmA family. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.622 |
| csrA | sun | ECA3366 | ECA4001 | Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Belongs to the CsrA/RsmA family. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.706 |
| infA | ECA0696 | ECA2653 | ECA0696 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | 0.493 |
| infA | sun | ECA2653 | ECA4001 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.452 |
| nadD | ECA0696 | ECA1306 | ECA0696 | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative RNA-binding protein containing kh domain stm3298 or sty3476 SWALL:Q8XG58 (EMBL:AE008852) (110 aa) fasta scores: E(): 3.7e-30, 88.66% id in 97 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YhbY SWALL:YHBY_ECOLI (SWALL:P42550) (97 aa) fasta scores: E(): 5.2e-30, 88.66% id in 97 aa. | 0.752 |