STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
evrVirulence regulator; Similar to Pectobacterium carotovorum subsp. carotovorum virulence regulator Evr SWALL:AAN86997 (EMBL:AY167733) (204 aa) fasta scores: E(): 4.8e-39, 92.98% id in 114 aa. This CDS is truncated at the N-terminus relative to its orthologue in Pectobacterium carotovorum subsp. carotovorum. (116 aa)    
Predicted Functional Partners:
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
  
 
 0.959
hrpX
Two-component sensor kinase; Similar to Erwinia chrysanthemi HrpX SWALL:Q8KUM4 (EMBL:AF448202) (450 aa) fasta scores: E(): 3.4e-115, 68.25% id in 441 aa, and to Erwinia amylovora sensor kinase HrpX SWALL:Q9X3S8 (EMBL:AF083877) (494 aa) fasta scores: E(): 9.5e-100, 56.13% id in 481 aa.
 
 
 0.922
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
  
 
 0.893
uhpA
Two-component system response regulator protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri transcriptional regulatory protein UhpA or b3669 or c4593 or z5159 or ecs4606 or sf3792 SWALL:UHPA_ECOLI (SWALL:P10940) (196 aa) fasta scores: E(): 1.2e-29, 48.98% id in 196 aa.
  
   
 0.742
narL
Nitrate/nitrite response regulator; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri nitrate/nitrite response regulator protein NarL or FrdR or b1221 or c1681 or z1996 or ecs1726 or sf1224 SWALL:NARL_ECOLI (SWALL:P10957) (216 aa) fasta scores: E(): 2.2e-60, 80.46% id in 215 aa.
  
     0.720
rcsB
Two-component response regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
  
   
 0.705
hrpY
Two-component response regulator; Similar to Erwinia chrysanthemi HrpY SWALL:Q8KUM3 (EMBL:AF448202) (213 aa) fasta scores: E(): 6.8e-57, 75.94% id in 212 aa, and to Erwinia amylovora response regulator HrpY SWALL:Q9X3S9 (EMBL:AF083877) (213 aa) fasta scores: E(): 1.3e-51, 69.34% id in 212 aa.
  
     0.705
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
 
 
 0.652
narX
Nitrate/nitrite sensor kinase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri nitrate/nitrite sensor protein NarX or NarR or b1222 or z1998 or ecs1727 or sf1225 SWALL:NARX_ECOLI (SWALL:P10956) (598 aa) fasta scores: E(): 1.5e-115, 54.06% id in 603 aa.
 
 
 0.645
expA
Two-component response regulator; Similar to Erwinia carotovora ExpA protein SWALL:O50326 (EMBL:X95564) (218 aa) fasta scores: E(): 1.3e-77, 98.62% id in 218 aa, and to Escherichia coli, and Shigella flexneri response regulator UvrY or b1914 or sf1957 SWALL:UVRY_ECOLI (SWALL:P07027) (218 aa) fasta scores: E(): 3.5e-65, 83.87% id in 217 aa. The Erwinia carotovora ExpA is involved in the global control of virulence.
  
   
 0.645
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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