Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rimIRibosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (147 aa)    
Predicted Functional Partners:
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
  
 0.922
rsmC
Ribosomal RNA small subunit methyltransferase C; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.
  
    0.549
ECA3957
Putative hydrolase; Similar to Clostridium perfringens hypothetical protein Cpe0762 cpe0762 SWALL:Q8XMC7 (EMBL:AP003188) (230 aa) fasta scores: E(): 2.8e-26, 34.8% id in 227 aa, and to Bacillus subtilis YfnB yfnB SWALL:O06480 (EMBL:D86418) (235 aa) fasta scores: E(): 5e-24, 34.34% id in 230 aa.
  
    0.535
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
      
 0.525
ECA2374
Similar to Yersinia pestis hypothetical protein Ypo2072 SWALL:Q8ZET1 (EMBL:AJ414151) (232 aa) fasta scores: E(): 1.3e-62, 72.84% id in 232 aa, and to Escherichia coli hypothetical protease yeaz yeaz or b1807 SWALL:YEAZ_ECOLI (SWALL:P76256) (231 aa) fasta scores: E(): 2.8e-59, 69.13% id in 230 aa.
 
 
 0.505
prfC
Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
  
  
 0.468
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
 
   
 0.468
ECA0732
Similar to Yersinia pestis putative exported protein ypo3993 SWALL:Q8ZA27 (EMBL:AJ414160) (159 aa) fasta scores: E(): 4.2e-40, 67.08% id in 158 aa.
       0.443
rimJ
Ribosomal-protein-alanine acetyltransferase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri ribosomal-protein-alanine acetyltransferase RimJ or b1066 or z1703 or ecs1444 or sf1072 SWALL:RIMJ_ECOLI (SWALL:P09454) (194 aa) fasta scores: E(): 3.3e-67, 77.31% id in 194 aa.
  
 
 0.441
ECA3012
Probable acetyltransferase; Similar to Escherichia coli ribosomal-protein-serine acetyltransferase RimL or b1427 SWALL:RIML_ECOLI (SWALL:P13857) (179 aa) fasta scores: E(): 3.6e-16, 38.88% id in 162 aa, and to Shigella flexneri acetylation of N-terminal serine of 30S ribosomal subunit protein l7, acetyl transferase RimL or sf1783 SWALL:AAN43352 (EMBL:AE015198) (183 aa) fasta scores: E(): 9.1e-18, 38.98% id in 177 aa.
  
 
 0.435
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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