STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ECA0747Putative short chain dehydrogenase; Similar to Agrobacterium tumefaciens NAD/NADP dependent oxidoreductase atu5391 or agr_pat_564 SWALL:Q8UJT4 (EMBL:AE008960) (286 aa) fasta scores: E(): 4.9e-43, 52.4% id in 250 aa, and to Bradyrhizobium japonicum oxidoreductase bll5108 SWALL:BAC50373 (EMBL:AP005953) (281 aa) fasta scores: E(): 1e-29, 43.21% id in 243 aa. (246 aa)    
Predicted Functional Partners:
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
  
 0.893
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
   
 0.852
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 0.839
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
     
 0.703
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
   0.692
ECA1905
Short chain dehydrogenase; Similar to Pseudomonas putida oxidoreductase, short chain dehydrogenase/reductase family pp2989 SWALL:AAN68597 (EMBL:AE016785) (264 aa) fasta scores: E(): 7.5e-67, 74.71% id in 261 aa, and to Agrobacterium tumefaciens short-chain dehydrogenase atu5444 or agr_pat_651 SWALL:Q8UJN2 (EMBL:AE008965) (287 aa) fasta scores: E(): 4.6e-55, 64.86% id in 259 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
  0.657
cfa7
Similar to Pseudomonas syringae type I polyketide synthase Cfa7 SWALL:Q9Z3T8 (EMBL:AF098795) (2066 aa) fasta scores: E(): 0, 52.6% id in 2091 aa, and to Streptomyces coelicolor putative type I polyketide synthase sco6275 SWALL:CAD55506 (EMBL:AL939127) (4557 aa) fasta scores: E(): 3e-183, 44.33% id in 1845 aa.
   
 0.561
entB
Enterobactin synthetase component B (isochorismatase); Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri isochorismatase EntB or EntG or b0595 or z0737 or ecs0634 or sf0509 SWALL:ENTB_ECOLI (SWALL:P15048) (285 aa) fasta scores: E(): 1.1e-69, 63.63% id in 286 aa.
  
 
 0.558
ECA0746
Similar to Bradyrhizobium japonicum transcriptional regulatory protein bll5370 SWALL:BAC50635 (EMBL:AP005954) (128 aa) fasta scores: E(): 2.4e-12, 48.51% id in 101 aa, and to Anabaena sp. hypothetical proteinalr2106 SWALL:Q8YV75 (EMBL:AP003588) (110 aa) fasta scores: E(): 6e-12, 41.5% id in 106 aa. Note that there are no significant database matches to enterobacterial species.
       0.544
fadB
Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 0.510
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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