STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerDIntegrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the b [...] (299 aa)    
Predicted Functional Partners:
recJ
Similar to Escherichia coli single-stranded-DNA-specific exonuclease RecJ SWALL:RECJ_ECOLI (SWALL:P21893) (577 aa) fasta scores: E(): 3.5e-163, 71.03% id in 580 aa, and to Erwinia chrysanthemi single-stranded-DNA-specific exonuclease RecJ SWALL:RECJ_ERWCH (SWALL:P39693) (575 aa) fasta scores: E(): 6.8e-178, 78.44% id in 580 aa.
     
 0.745
dsbC
Thiol:disulfide interchange protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
 
    0.630
recR
Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
   
 0.575
argR
Arginine repressor; Regulates arginine biosynthesis genes.
      
 0.557
uvrD
DNA helicase II; Similar to Escherichia coli DNA helicase II UvrD or MutU or PdeB or Rad or RecL or b3813 SWALL:UVRD_ECOLI (SWALL:P03018) (720 aa) fasta scores: E(): 0, 88.61% id in 720 aa.
      
 0.554
ECA2308
Putative phage-related protein; Similar to Culex nigripalpus baculovirus Cun001 putative bro protein, atp_gtp_a motif, similar to acmnpv orf 2 cun001 SWALL:Q919R4 (EMBL:AF403738) (593 aa) fasta scores: E(): 0.047, 23.98% id in 246 aa, and to Spodoptera frugiperda ascovirus 1 av1-bro-l10 protein SWALL:Q8JJX7 (EMBL:AJ312699) (268 aa) fasta scores: E(): 0.092, 23.92% id in 209 aa.
     
 0.546
intB
Phage integrase; Similar to Yersinia pestis integrase IntB or ypo3438 SWALL:Q8ZBH6 (EMBL:AJ414157) (419 aa) fasta scores: E(): 2.4e-97, 58.15% id in 423 aa, and to Shigella flexneri integrase IntB or sf4224 SWALL:AAN45643 (EMBL:AE015430) (415 aa) fasta scores: E(): 2.4e-90, 58.45% id in 402 aa; Belongs to the 'phage' integrase family.
      
 0.544
ccmB
Heme exporter protein B; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
      
 0.544
ECA3460
Phage integrase; Similar to Escherichia coli O157:H7 integrase protein for prophage CP-933i z0324 or ecs0289 SWALL:Q8X7K7 (EMBL:AE005203) (410 aa) fasta scores: E(): 7.6e-123, 75.3% id in 405 aa, and to Yersinia pestis putative phage integrase ypo4033 or y4052 SWALL:AAM87596 (EMBL:AJ414160) (397 aa) fasta scores: E(): 1.5e-94, 62.67% id in 367 aa; Belongs to the 'phage' integrase family.
      
 0.544
mobB
Similar to Escherichia coli molybdopterin-guanine dinucleotide biosynthesis protein B MobB SWALL:MOBB_ECOLI (SWALL:P32125) (174 aa) fasta scores: E(): 1.2e-34, 64.84% id in 165 aa.
      
 0.542
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.