STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
actPPutative sodium:solute symporter; Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (552 aa)    
Predicted Functional Partners:
ECA0807
Putative membrane protein; Similar to Escherichia coli, and Shigella flexneri hypothetical protein YjcH SWALL:YJCH_ECOLI (SWALL:P32706) (104 aa) fasta scores: E(): 7.3e-27, 71.56% id in 102 aa, and to Salmonella typhi putative membrane protein sty4472 SWALL:Q8Z1R1 (EMBL:AL627282) (104 aa) fasta scores: E(): 1.7e-25, 70.58% id in 102 aa.
 
  
 0.998
ECA4501
Similar to Escherichia coli O157:H7 putative enzyme z4856 or ecs4331 SWALL:Q8X6M3 (EMBL:AE005571) (453 aa) fasta scores: E(): 3.5e-72, 46.3% id in 447 aa, and to Vibrio vulnificus acyl-coenzyme A synthetase vv10050 SWALL:Q8DG01 (EMBL:AE016797) (455 aa) fasta scores: E(): 9.7e-48, 37.86% id in 441 aa.
  
  
 0.654
fadB
Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
  
 0.582
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
      
 0.568
ECA0293
Similar to Yersinia pestis hypothetical protein ypo3577 SWALL:Q8ZB48 (EMBL:AJ414157) (328 aa) fasta scores: E(): 2e-101, 81.59% id in 326 aa, and to Escherichia coli hypothetical protein Yrbh SWALL:YRBH_ECOLI (SWALL:P45395) (328 aa) fasta scores: E(): 2e-95, 78.08% id in 324 aa.
  
  
 0.498
fadJ
Putative fatty acid oxidation complex alpha subunit; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.452
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
   
  
 0.442
ECA0805
Similar to Salmonella typhi hypothetical protein sty4288 SWALL:Q8Z220 (EMBL:AL627281) (308 aa) fasta scores: E(): 3.3e-57, 51.82% id in 301 aa, and to Erwinia amylovora hypothetical 37.6 kDa protein SWALL:Q9F805 (EMBL:AF264948) (332 aa) fasta scores: E(): 2.9e-54, 48.67% id in 302 aa, and to Escherichia coli hypothetical protein YfaD SWALL:YFAD_ECOLI (SWALL:P37014) (299 aa) fasta scores: E(): 8.6e-48, 47.82% id in 299 aa.
       0.421
aceA
Isocitrate lyase; Similar to Escherichia coli, and Escherichia coli O6 isocitrate lyase AceA or Icl or b4015 or c4972 SWALL:ACEA_ECOLI (SWALL:P05313) (434 aa) fasta scores: E(): 4.7e-157, 86.8% id in 432 aa.
   
  
 0.403
aceB
Similar to Escherichia coli malate synthase A AceB or Mas or b4014 SWALL:MASY_ECOLI (SWALL:P08997) (533 aa) fasta scores: E(): 6.4e-180, 82.04% id in 529 aa.
   
  
 0.401
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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