node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cobB | mazG | ECA1827 | ECA3568 | Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily. | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | 0.901 |
cobB | nadD | ECA1827 | ECA1306 | Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily. | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.934 |
cobB | nadE | ECA1827 | ECA2412 | Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily. | NH3-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.931 |
cobB | nadR | ECA1827 | ECA0463 | Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily. | Similar to Salmonella typhimurium transcriptional regulator NadR SWALL:NADR_SALTY (SWALL:P24518) (410 aa) fasta scores: E(): 1.1e-140, 85.5% id in 407 aa, and to Escherichia coli transcriptional regulator NadR or NadI or b4390 SWALL:NADR_ECOLI (SWALL:P27278) (410 aa) fasta scores: E(): 2.2e-139, 83.9% id in 410 aa. | 0.992 |
cobB | nudC | ECA1827 | ECA0234 | Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily. | Similar to Escherichia coli NADH pyrophosphatase NudC SWALL:NUDC_ECOLI (SWALL:P32664) (257 aa) fasta scores: E(): 2.2e-77, 70.42% id in 257 aa, and to Yersinia pestis NADH pyrophosphatase NudC SWALL:NUDC_YERPE (SWALL:Q8ZAQ5) (260 aa) fasta scores: E(): 1.3e-84, 75.87% id in 257 aa. | 0.905 |
cobB | pntA | ECA1827 | ECA2204 | Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily. | Pyridine nucleotide transhydrogenase subunit-alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.910 |
cobB | pntB | ECA1827 | ECA2205 | Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily. | Pyridine nucleotide transhydrogenase subunit-beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.901 |
cobB | ppnK | ECA1827 | ECA0841 | Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.929 |
cobB | sthA | ECA1827 | ECA4242 | Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.915 |
mazG | cobB | ECA3568 | ECA1827 | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily. | 0.901 |
mazG | nadD | ECA3568 | ECA1306 | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.904 |
mazG | nadE | ECA3568 | ECA2412 | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | NH3-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.900 |
mazG | nadR | ECA3568 | ECA0463 | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | Similar to Salmonella typhimurium transcriptional regulator NadR SWALL:NADR_SALTY (SWALL:P24518) (410 aa) fasta scores: E(): 1.1e-140, 85.5% id in 407 aa, and to Escherichia coli transcriptional regulator NadR or NadI or b4390 SWALL:NADR_ECOLI (SWALL:P27278) (410 aa) fasta scores: E(): 2.2e-139, 83.9% id in 410 aa. | 0.905 |
mazG | nudC | ECA3568 | ECA0234 | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | Similar to Escherichia coli NADH pyrophosphatase NudC SWALL:NUDC_ECOLI (SWALL:P32664) (257 aa) fasta scores: E(): 2.2e-77, 70.42% id in 257 aa, and to Yersinia pestis NADH pyrophosphatase NudC SWALL:NUDC_YERPE (SWALL:Q8ZAQ5) (260 aa) fasta scores: E(): 1.3e-84, 75.87% id in 257 aa. | 0.911 |
mazG | pntA | ECA3568 | ECA2204 | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | Pyridine nucleotide transhydrogenase subunit-alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.901 |
mazG | pntB | ECA3568 | ECA2205 | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | Pyridine nucleotide transhydrogenase subunit-beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.902 |
mazG | ppnK | ECA3568 | ECA0841 | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.903 |
mazG | sthA | ECA3568 | ECA4242 | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.919 |
nadD | cobB | ECA1306 | ECA1827 | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily. | 0.934 |
nadD | mazG | ECA1306 | ECA3568 | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | 0.904 |