STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lerKPutative dihydroxyacetone kinase; Involved in catabolism of D-apiose. Catalyzes the phosphorylation of L-erythrulose to L-erythrulose 1-phosphate. Can also phosphorylate D-erythrulose and dihydroxyacetone in vitro. (590 aa)    
Predicted Functional Partners:
oiaC
Conserved hypothetical protein; Involved in catabolism of D-apiose. Catalyzes decarboxylation of 3-oxo-isoapionate to L-erythrulose.
 
   
 0.957
tpiA
Putative triosephosphate isomerase; Involved in catabolism of D-apiose. Catalyzes the isomerization of L-erythrulose 1-phosphate to D-erythrulose 4- phosphate.
 
  
 0.954
apnO
Conserved hypothetical protein; Involved in catabolism of D-apiose. Catalyzes the conversion of D-apionate to 3-oxo-isoapionate.
 
   
 0.946
ECA0865
Probable transport protein; Similar to Streptomyces coelicolor putative transporter protein sco0581 SWALL:Q9RJQ9 (EMBL:AL939106) (455 aa) fasta scores: E(): 2.9e-116, 68.09% id in 442 aa, and to Yersinia pestis putative integral membrane protein ypo2237 SWALL:Q8ZED7 (EMBL:AJ414151) (436 aa) fasta scores: E(): 3.1e-61, 39.77% id in 435 aa.
 
     0.850
rpiB
Ribose 5-phosphate isomerase; Involved in catabolism of D-apiose. Catalyzes the isomerization of D-erythrulose 4-phosphate to D-erythrose 4-phosphate.
 
   
 0.805
ECA0864
Hypothetical protein; No significant database matches.
       0.773
ECA0870
Similar to Yersinia pestis putative transcriptional regulator y0843 SWALL:AAM84428 (EMBL:AE013687) (332 aa) fasta scores: E(): 8e-99, 83.12% id in 320 aa, and to Klebsiella pneumoniae sorbitol operon regulator SorC SWALL:SORC_KLEPN (SWALL:P37078) (315 aa) fasta scores: E(): 6.1e-16, 30.03% id in 313 aa.
  
  0.769
aplK
Glycerol kinase; Involved in catabolism of D-apiose. Catalyzes phosphorylation of apulose to form apulose 4-phosphate.
     
 0.619
apsI
Putative xylose isomerase; Involved in catabolism of D-apiose. Catalyzes isomerization of D-apiose to apulose.
  
   
 0.618
glpA
Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri anaerobic glycerol-3-phosphate dehydrogenase subunit A GlpA or b2241 or z3499 or ecs3126 or sf2323 SWALL:GLPA_ECOLI (SWALL:P13032) (542 aa) fasta scores: E(): 1.1e-153, 72.34% id in 546 aa; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 
 0.608
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (26%) [HD]