STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtrTryptophan-specific transport protein; Similar to Escherichia coli, and Shigella flexneri tryptophan-specific transport protein Mtr or b3161 or sf3202 SWALL:MTR_ECOLI (SWALL:P22306) (414 aa) fasta scores: E(): 1.8e-121, 74.08% id in 409 aa. (424 aa)    
Predicted Functional Partners:
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 0.588
trpR
Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
  
   
 0.564
ECA1474
Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein year or b1797 or z2839 or ecs2506 SWALL:YEAR_ECOLI (SWALL:P76248) (119 aa) fasta scores: E(): 3.1e-30, 66.66% id in 105 aa, and to Salmonella typhi hypothetical protein Sty1850 SWALL:Q8Z6D6 (EMBL:AL627271) (120 aa) fasta scores: E(): 5.8e-30, 65.71% id in 105 aa.
  
     0.544
ECA0692
Similar to Yersinia pestis putative membrane protein ypo3510 SWALL:AAM84262 (EMBL:AJ414157) (328 aa) fasta scores: E(): 3e-95, 78.77% id in 311 aa, and to Salmonella typhi putative membrane protein sty3481 SWALL:Q8Z3H0 (EMBL:AL627278) (321 aa) fasta scores: E(): 1.3e-92, 77.24% id in 312 aa.
  
   
 0.514
menC
O-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
  
     0.456
putA
Bifunctional PutA protein [includes: proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
  
 0.456
ECA0009
Putative exported protein; Similar to Salmonella typhimurium, and Salmonella typhi putative outer membrane proteinYgiW or stm3176 or sty3353 SWALL:Q8XGT5 (EMBL:AE008846) (130 aa) fasta scores: E(): 1.8e-27, 63.35% id in 131 aa, and to Yersinia pestis putative exported protein ypo3027 or y1455 SWALL:Q8ZCG4 (EMBL:AJ414155) (137 aa) fasta scores: E(): 1.4e-20, 50.73% id in 136 aa.
  
     0.413
maeB
Similar to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 0, 84.32% id in 759 aa.
  
  
 0.408
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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