Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ECA0878Similar to Escherichia coli hypothetical protein yddb or b1495 SWALL:YDDB_ECOLI (SWALL:P31827) (790 aa) fasta scores: E(): 6.7e-27, 28.16% id in 813 aa, and to Haemophilus influenzae hypothetical protein Hi1369 SWALL:YDDB_HAEIN (SWALL:P45182) (839 aa) fasta scores: E(): 6.1e-19, 24.43% id in 843 aa. (860 aa)    
Predicted Functional Partners:
ECA0877
TonB-like protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
   0.672
ECA0880
Putative ABC transporter ATP-binding protein; Similar to Pasteurella multocida hypothetical protein Pm0041 SWALL:Q9CPJ6 (EMBL:AE006038) (564 aa) fasta scores: E(): 7.9e-99, 48.01% id in 554 aa, and to Escherichia coli hypothetical ABC transporter ATP-binding protein YddA SWALL:YDDA_ECOLI (SWALL:P31826) (561 aa) fasta scores: E(): 5.7e-71, 38.24% id in 536 aa.
       0.560
ECA0879
Putative zinc protease; Similar to Escherichia coli probable zinc protease PqqL or b1494 SWALL:PQQL_ECOLI (SWALL:P31828) (931 aa) fasta scores: E(): 1.1e-43, 25.42% id in 948 aa, and to Pasteurella multocida PqqL or pm0804 SWALL:Q9CML5 (EMBL:AE006119) (923 aa) fasta scores: E(): 1.9e-47, 23.52% id in 948 aa; deleted EC_number 3.4.99.-; Belongs to the peptidase M16 family.
  
    0.559
rspA
Putative starvation sensing mandelate racemase / muconate lactonizing enzyme; Similar to Escherichia coli starvation sensing protein RspA SWALL:RSPA_ECOLI (SWALL:P38104) (404 aa) fasta scores: E(): 5.7e-163, 92.57% id in 404 aa. Also similar to ECA0189 (36.070% id. in 402 aa overlap).
      
 0.530
secD
Protein-export membrane protei; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
      
 0.530
imp
Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
      
 0.530
fusA
Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
      
 0.530
ompA
Outer-membrane protein A; Similar to Erwinia carotovora putative outer-membrane protein a precursor OmpA SWALL:Q9RM69 (EMBL:AJ249340) (367 aa) fasta scores: E(): 2.6e-120, 90.32% id in 372 aa, and to Serratia marcescens outer membrane protein a precursor OmpA SWALL:OMPA_SERMA (SWALL:P04845) (359 aa) fasta scores: E(): 4.8e-71, 75.61% id in 369 aa; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
     
 0.523
ECA3178
Similar to Pseudomonas fluorescens arabinogalactan endo-1,4-beta-galactosidase precursor GalA or GanA SWALL:GANA_PSEFL (SWALL:P48841) (376 aa) fasta scores: E(): 3.5e-35, 33.98% id in 409 aa, and to Yersinia pestis putative galactosidase ypo0853 or y3238 SWALL:Q8ZHN7 (EMBL:AJ414145) (400 aa) fasta scores: E(): 2.1e-117, 72.51% id in 393 aa.
      
 0.499
ECA0852
Putative exported plant proteoglycan hydrolase; Similar to Pseudomonas fluorescens arabinogalactan endo-1,4-beta-galactosidase precursor gala or ganA SWALL:GANA_PSEFL (SWALL:P48841) (376 aa) fasta scores: E(): 1.2e-16, 33.53% id in 325 aa, and to Thermotoga maritima arabinogalactan endo-1,4-beta-galactosidase, putative tm1201 SWALL:Q9X0S8 (EMBL:AE001777) (606 aa) fasta scores: E(): 1.6e-33, 36.2% id in 348 aa, and to Aspergillus aculeatus arabinogalactan endo-1,4-beta-galactosidase precursor gal1 SWALL:GANA_ASPAC (SWALL:P48842) (350 aa) fasta scores: E(): 2.2e-15, 30.69% id in 329 aa.
      
 0.496
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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