STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA0889Two-component system response regulator; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri transcriptional regulatory protein CpxR or b3912 or z5457 or ecs4838 or sf3991 SWALL:CPXR_ECOLI (SWALL:P16244) (232 aa) fasta scores: E(): 3.5e-31, 44.93% id in 227 aa, and to Yersinia pestis putative two-component system response regulator ypo2998 or cpxr or y1482 SWALL:Q8ZCI9 (EMBL:AJ414154) (227 aa) fasta scores: E(): 1.3e-67, 77.97% id in 227 aa. (226 aa)    
Predicted Functional Partners:
ECA0890
Two-component system sensor kinase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 sensor protein CpxA or EcfB or Ssd or Eup or b3911 or c4863 or z5456 or ecs4837 SWALL:CPXA_ECOLI (SWALL:P08336) (457 aa) fasta scores: E(): 2.2e-23, 29.53% id in 474 aa, and to Yersinia pestis putative two-component system sensor kinase ypo2997 or y1483 SWALL:Q8ZCJ0 (EMBL:AJ414154) (449 aa) fasta scores: E(): 1e-91, 56.86% id in 459 aa.
 
 
 0.975
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
 
0.951
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
 
 
 0.892
cpxA
Two-component sensor kinase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 sensor protein CpxA or EcfB or Ssd or Eup or b3911 or c4863 or z5456 or ecs4837 SWALL:CPXA_ECOLI (SWALL:P08336) (457 aa) fasta scores: E(): 1.8e-151, 80.04% id in 456 aa.
 
 0.870
pmrB
Two-component sensor kinase; Similar to Pectobacterium carotovorum subsp. carotovorum sensor kinase PmrB SWALL:CAE47080 (EMBL:AJ583007) (364 aa) fasta scores: E(): 1.5e-125, 94.78% id in 364 aa, and to Escherichia coli sensor protein BasS or PmrB or b4112 SWALL:BASS_ECOLI (SWALL:P30844) (363 aa) fasta scores: E(): 9.5e-69, 58.64% id in 353 aa.
 
 
 0.795
ECA0786
Two component system sensor kinase; Similar to Pseudomonas putida sensor histidine kinase pp2906 SWALL:AAN68514 (EMBL:AE016784) (463 aa) fasta scores: E(): 2.3e-32, 30.91% id in 427 aa, and to Rhizobium loti sensory histidine protein kinase mlr4459 SWALL:Q98E08 (EMBL:AP003004) (458 aa) fasta scores: E(): 1.2e-30, 31.25% id in 464 aa.
 
 0.777
baeS
Two-component system sensor kinase; Similar to Escherichia coli sensor protein BaeS or b2078 SWALL:BAES_ECOLI (SWALL:P30847) (467 aa) fasta scores: E(): 3.1e-113, 65.06% id in 458 aa.
 
 0.725
envZ
Similar to Salmonella typhi osmolarity sensor protein envz envz or sty4295 or t4005 SWALL:ENVZ_SALTI (SWALL:P41406) (450 aa) fasta scores: E(): 2.2e-144, 84.1% id in 434 aa.
 
 
 0.723
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
   0.694
qseC
Two-component system sensor kinase; Similar to Escherichia coli sensor protein QseC SWALL:QSEC_ECOLI (SWALL:P40719) (449 aa) fasta scores: E(): 7.4e-94, 56.15% id in 447 aa.
 
 
 0.673
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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