STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tehBSimilar to Escherichia coli tellurite resistance protein TehB or b1430 SWALL:TEHB_ECOLI (SWALL:P25397) (197 aa) fasta scores: E(): 3.4e-41, 60.73% id in 191 aa, and to Yersinia pestis tehb protein TehB or ypo1949 or y2361 SWALL:Q9ZC59 (EMBL:AL031866) (295 aa) fasta scores: E(): 3.3e-81, 70.21% id in 282 aa. (286 aa)    
Predicted Functional Partners:
hmpX
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
  
  
 0.657
ECA1472
Conserved hypothetical protein; Similar to Salmonella enterica subsp. enterica serovar Typhi Ty2 hypothetical protein T1150 t1150 SWALL:AAO68810 (EMBL:AE016838) (60 aa) fasta scores: E(): 2.6e-06, 52.72% id in 55 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yoag or b1796 or c2202 or z2838 or ecs2505 SWALL:YOAG_ECOLI (SWALL:P76247) (60 aa) fasta scores: E(): 7.9e-06, 49.09% id in 55 aa.
  
  
 0.590
ECA3377
Glutaredoxin; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 glutaredoxin 2 grxb or b1064 or c1331 or z1701 or ecs1442 SWALL:GLR2_ECOLI (SWALL:P39811) (215 aa) fasta scores: E(): 3.6e-31, 44.44% id in 216 aa. Also similar to ECA2526 (42.593% id. in 216 aa overlap).
  
     0.557
ppdA
Similar to Escherichia coli prepilin peptidase dependent protein A precursor PpdA or b2826 SWALL:PPDA_ECOLI (SWALL:P33554) (156 aa) fasta scores: E(): 5.2e-19, 40% id in 150 aa, and to Salmonella typhimurium prepilin peptidase dependent protein a, putative component in type IVpilin biogenesis ppda or stm3000 SWALL:Q8ZMB0 (EMBL:AE008837) (156 aa) fasta scores: E(): 2.7e-20, 39.35% id in 155 aa.
  
     0.542
ppx
Exopolyphosphatase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 exopolyphosphatase Ppx or b2502 or c3020 or z3765 or ecs3364 SWALL:PPX_ECOLI (SWALL:P29014) (512 aa) fasta scores: E(): 8.4e-153, 75.3% id in 498 aa; Belongs to the GppA/Ppx family.
 
      0.527
ppdD
Similar to Escherichia coli prepilin peptidase dependent protein D precursor PpdD or b0108 SWALL:PPDD_ECOLI (SWALL:P36647) (146 aa) fasta scores: E(): 2.8e-32, 60.69% id in 145 aa.
  
     0.526
norV
Anaerobic nitric oxide reductase flavorubredoxin; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family.
  
  
 0.519
grxB
Glutaredoxin 2; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 glutaredoxin 2 GrxB or b1064 or c1331 or z1701 or ecs1442 SWALL:GLR2_ECOLI (SWALL:P39811) (215 aa) fasta scores: E(): 4.6e-60, 69.76% id in 215 aa. Also similar to ECA3377 (42.593% id. in 216 aa overlap).
  
     0.489
pgpB
Phosphatidylglycerophosphatase B; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri phosphatidylglycerophosphatase B PgpB or b1278 or z2529 or ecs1851 or sf1282 SWALL:PGPB_ECOLI (SWALL:P18201) (254 aa) fasta scores: E(): 6.1e-68, 61.75% id in 251 aa.
  
     0.441
ECA1510
Putative iron permease; Similar to Yersinia pestis similarity to some hypothetical proteins in b. subtilis ypo1941 or y2370 SWALL:Q9ZC51 (EMBL:AL031866) (639 aa) fasta scores: E(): 5.2e-172, 74.02% id in 639 aa, and to Pasteurella multocida hypothetical protein Pm0453 pSWALL:Q9CNH8 (EMBL:AE006081) (634 aa) fasta scores: E(): 9.6e-146, 64.36% id in 623 aa.
  
     0.431
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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