STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Coexpression
Experiments
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[Homology]
Score
fumAFumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (547 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 
 0.997
sdhD
Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
 
 0.986
ECA0910
Similar to Shewanella frigidimarina fumarate reductase flavoprotein subunit precursor FccA or Fcc3 SWALL:FRDA_SHEFR (SWALL:Q02469) (596 aa) fasta scores: E(): 1e-20, 27.82% id in 496 aa, and to Shewanella oneidensis fumarate reductase flavoprotein subunit precursor so0970 SWALL:FRDA_SHEON (SWALL:P83223) (596 aa) fasta scores: E(): 1.7e-17, 29.27% id in 485 aa, and to Rhodococcus erythropolis 3-ketosteroid 1-dehydrogenase KstD2 SWALL:Q8RLT5 (EMBL:AY078169) (565 aa) fasta scores: E(): 5e-10, 28.73% id in 341 aa.
  
 
 0.981
sdhA
Succinate dehydrogenase flavoprotein subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 succinate dehydrogenase flavoprotein subunit SdhA or b0723 or c0801 or z0877 or ecs0748 SWALL:DHSA_ECOLI (SWALL:P10444) (588 aa) fasta scores: E(): 0, 93.19% id in 588 aa; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
 0.981
ECA1969
Putative NADH:flavin oxidoreductase; The C-terminal region of this CDS is similar to Shewanella frigidimarina fumarate reductase flavoprotein subunit precursor FccA or Fcc3 SWALL:FRDA_SHEFR (SWALL:Q02469) (596 aa) fasta scores: E(): 2.7e-64, 43.72% id in 462 aa, and to Staphylococcus epidermidis putative NADH-dependent flavin oxidoreductase se0195 SWALL:AAO03792 (EMBL:AE016744) (1005 aa) fasta scores: E(): 2.2e-69, 38.82% id in 1007 aa.
  
 
 0.981
frdA
Similar to Escherichia coli fumarate reductase flavoprotein subunit FrdA or b4154 SWALL:FRDA_ECOLI (SWALL:P00363) (601 aa) fasta scores: E(): 4.9e-203, 84.52% id in 601 aa.
  
 
 0.981
sdhB
Similar to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB or b0724 SWALL:DHSB_ECOLI (SWALL:P07014) (238 aa) fasta scores: E(): 6.3e-88, 87.81% id in 238 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.979
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.979
frdB
Fumarate reductase iron-sulfur protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri fumarate reductase iron-sulfur protein frdB or b4153 or c5241 or z5760 or ecs5134 or sf4311 SWALL:FRDB_ECOLI (SWALL:P00364) (243 aa) fasta scores: E(): 2.8e-84, 85.24% id in 244 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.979
icd
Similar to Escherichia coli isocitrate dehydrogenase [NADP] Icd or IcdA or IcdE or b1136 SWALL:IDH_ECOLI (SWALL:P08200) (416 aa) fasta scores: E(): 1.7e-143, 88.01% id in 417 aa.
  
  
 0.977
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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