STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adaSimilar to Escherichia coli Ada regulatory protein SWALL:ADA_ECOLI (SWALL:P06134) (354 aa) fasta scores: E(): 2.3e-70, 53.95% id in 341 aa. (371 aa)    
Predicted Functional Partners:
ECA0907
Similar to Schizosaccharomyces pombe DNA-3-methyladenine glycosylase 1 Mag1 or spapb24d3.04C SWALL:MAG1_SCHPO (SWALL:Q92383) (228 aa) fasta scores: E(): 3.5e-33, 43.75% id in 208 aa, and to Pseudomonas putida DNA-3-methyladenine glycosylase pp0705 SWALL:AAN66330 (EMBL:AE016776) (208 aa) fasta scores: E(): 1.7e-39, 51.98% id in 202 aa.
 
 
 0.946
alkB
Similar to Escherichia coli alkylated DNA repair protein AlkB or AidD or b2212 SWALL:ALKB_ECOLI (SWALL:P05050) (216 aa) fasta scores: E(): 6e-49, 56.94% id in 216 aa.
 
  
 0.934
polA
Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.715
rpoD
RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.693
rpoS
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
   
 
 0.693
rpoH
RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
   
 
 0.693
ECA2558
Similar to Yersinia pestis putative membrane protein ypo1394 or y2778 SWALL:Q8ZGB0 (EMBL:AJ414148) (763 aa) fasta scores: E(): 7.2e-161, 50.19% id in 763 aa, and to Salmonella typhi putative competence-related protein sty0984 SWALL:Q8Z802 (EMBL:AL627268) (754 aa) fasta scores: E(): 7.2e-126, 42.52% id in 762 aa.
     
 0.672
recA
RecA protein (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.663
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
  
 0.607
recO
DNA repair protein; Involved in DNA repair and RecF pathway recombination.
     
 0.555
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.