STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fhuETonB-dependent receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid; Similar to Escherichia coli FhuE receptor precursor FhuE or b1102 SWALL:FHUE_ECOLI (SWALL:P16869) (729 aa) fasta scores: E(): 1.9e-162, 55.86% id in 725 aa. (737 aa)    
Predicted Functional Partners:
fepA
TonB dependent siderophore receptor; Similar to Escherichia coli ferrienterobactin receptor precursor FepA or Fep or FeuB or b0584 SWALL:FEPA_ECOLI (SWALL:P05825) (746 aa) fasta scores: E(): 1.6e-186, 63.68% id in 738 aa, and to Pseudomonas aeruginosa ferric enterobactin receptor precursor pfea or pa2688 SWALL:PFEA_PSEAE (SWALL:Q05098) (746 aa) fasta scores: E(): 1.1e-187, 66.1% id in 717 aa.
 
  
 0.720
ECA1272
TonB-like protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.617
ECA0058
Transmembrane sensor; Similar to Escherichia coli protein FecR or b4292 SWALL:FECR_ECOLI (SWALL:P23485) (317 aa) fasta scores: E(): 3.1e-33, 36.04% id in 319 aa.
 
  
 0.588
ECA2722
Exogenous ferric siderophore TonB-dependent receptor; Similar to Vibrio cholerae iron-regulated outer membrane virulence protein precursor IrgA or vc0475 SWALL:IRGA_VIBCH (SWALL:P27772) (652 aa) fasta scores: E(): 9.1e-29, 35.05% id in 716 aa, and to Escherichia coli exogenous ferric siderophore receptor R4 SWALL:O87518 (EMBL:AF081285) (669 aa) fasta scores: E(): 2e-148, 55.45% id in 678 aa, and to Campylobacter coli ferric receptor CfrA cfrA SWALL:O07651 (EMBL:U80812) (696 aa) fasta scores: E(): 2.3e-77, 37.83% id in 703 aa.
 
  
 0.571
ECA0928
TonB-like protein; Similar to Salmonella typhimurium TonB protein SWALL:TONB_SALTY (SWALL:P25945) (242 aa) fasta scores: E(): 6.8e-09, 35.93% id in 192 aa, and to Escherichia coli TonB protein SWALL:TONB_ECOLI (SWALL:P02929) (239 aa) fasta scores: E(): 6.5e-07, 37.91% id in 182 aa.
 
 
 0.568
ECA1273
Putative sensor protein; Similar to Escherichia coli protein FecR or b4292 SWALL:FECR_ECOLI (SWALL:P23485) (317 aa) fasta scores: E(): 2.9e-18, 30.09% id in 309 aa, and to Pseudomonas aeruginosa probable transmembrane sensor pa0471 SWALL:Q9I647 (EMBL:AE004485) (323 aa) fasta scores: E(): 8.9e-27, 32.58% id in 313 aa.
 
  
 0.563
tonB
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.563
fecR
iron(III) dicitrate sensor protein; Similar to Escherichia coli protein FecR or b4292 SWALL:FECR_ECOLI (SWALL:P23485) (317 aa) fasta scores: E(): 7.6e-87, 69.55% id in 312 aa, and to Shigella flexneri 2a FecR SWALL:AAL08457 (EMBL:AF326777) (317 aa) fasta scores: E(): 7.6e-87, 69.55% id in 312 aa.
 
  
 0.562
ECA1539
Similar to Pseudomonas aeruginosa probable transmembrane sensor pa3409 SWALL:Q9HYJ6 (EMBL:AE004762) (328 aa) fasta scores: E(): 2.2e-40, 42.68% id in 328 aa, and to Pseudomonas putida transmembrane sensor, putative pp4607 SWALL:AAN70180 (EMBL:AE016791) (326 aa) fasta scores: E(): 2.6e-25, 36.13% id in 321 aa.
 
  
 0.551
ECA0814
Putative iron sensor protein; Similar to Escherichia coli protein FecR SWALL:FECR_ECOLI (SWALL:P23485) (317 aa) fasta scores: E(): 4.1e-27, 33.01% id in 315 aa, and to Pseudomonas putida PupR protein SWALL:Q52209 (EMBL:X77918) (324 aa) fasta scores: E(): 3.3e-23, 29.9% id in 321 aa, and to Bordetella avium RhuR SWALL:Q8L1U8 (EMBL:AY095952) (307 aa) fasta scores: E(): 3.3e-17, 27.12% id in 317 aa.
 
  
 0.534
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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