STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speCSimilar to Escherichia coli ornithine decarboxylase, constitutive SpeC or b2965 SWALL:DCOR_ECOLI (SWALL:P21169) (711 aa) fasta scores: E(): 0, 71.78% id in 716 aa, and to Yersinia pestis ornithine decarboxylase SpeC or ypo0960 or y3347 SWALL:Q8ZHE0 (EMBL:AJ414145) (720 aa) fasta scores: E(): 0, 73.61% id in 720 aa. (717 aa)    
Predicted Functional Partners:
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 
 0.981
patA
Probable aminotransferase; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
  
 
 0.955
ECA4274
Similar to Yersinia pestis putative carbon-nitrogen hydrolase ypo0938 or y3324 SWALL:Q8ZHG1 (EMBL:AJ414145) (294 aa) fasta scores: E(): 2.8e-116, 93.87% id in 294 aa, and to Pseudomonas aeruginosa probable hydratase pa0293 SWALL:Q9I6J8 (EMBL:AE004467) (292 aa) fasta scores: E(): 4.5e-79, 65.05% id in 289 aa.
    
 0.952
rafA
Alpha-galactosidase; Similar to Escherichia coli alpha-galactosidase RafA SWALL:RAFA_ECOLI (SWALL:P16551) (708 aa) fasta scores: E(): 7.5e-208, 67.66% id in 705 aa.
      
 0.789
ECA1968
Putative glycosyl hydrolase; Similar to Yersinia pestis putative glucosidase ypo0848 or y3233 SWALL:Q8ZHP2 (EMBL:AJ414145) (792 aa) fasta scores: E(): 0, 76.27% id in 784 aa, and to Bacillus thermoamyloliquefaciens alpha-glucosidase II SWALL:AGL2_BACTQ (SWALL:Q9F234) (787 aa) fasta scores: E(): 1.5e-66, 27.93% id in 784 aa; Belongs to the glycosyl hydrolase 31 family.
      
 0.789
ECA3497
Similar to Xanthomonas axonopodis gamma-glutamyltranspeptidase Ggt or xac0305 SWALL:Q8PQL8 (EMBL:AE011655) (526 aa) fasta scores: E(): 1.1e-98, 53.01% id in 530 aa, and to Vibrio cholerae gamma-glutamyltranspeptidase, putative vca0558 SWALL:Q9KM31 (EMBL:AE004386) (522 aa) fasta scores: E(): 2.1e-82, 48.24% id in 514 aa.
      
 0.789
ggt
Similar to Escherichia coli gamma-glutamyltranspeptidase precursor Ggt or b3447 SWALL:GGT_ECOLI (SWALL:P18956) (580 aa) fasta scores: E(): 2.3e-93, 46.93% id in 571 aa, and to Pseudomonas sp. gamma-glutamyltranspeptidase precursor Ggt SWALL:GGT_PSESP (SWALL:P36267) (575 aa) fasta scores: E(): 1.2e-114, 56.17% id in 591 aa.
      
 0.789
ravA
Conserved hypothetical protein; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone; Belongs to the RavA family.
   
 
 0.741
aguA
Similar to Yersinia pestis hypothetical protein Ypo0939 SWALL:Q8ZHG0 (EMBL:AJ414145) (371 aa) fasta scores: E(): 1.3e-117, 75.47% id in 367 aa, and to Shewanella oneidensis conserved hypothetical protein so0887 SWALL:AAN53963 (EMBL:AE015534) (349 aa) fasta scores: E(): 3.9e-99, 67.33% id in 349 aa.
    
 0.679
speA
Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine.
     
 0.670
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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