STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speCSimilar to Escherichia coli ornithine decarboxylase, constitutive SpeC or b2965 SWALL:DCOR_ECOLI (SWALL:P21169) (711 aa) fasta scores: E(): 0, 71.78% id in 716 aa, and to Yersinia pestis ornithine decarboxylase SpeC or ypo0960 or y3347 SWALL:Q8ZHE0 (EMBL:AJ414145) (720 aa) fasta scores: E(): 0, 73.61% id in 720 aa. (717 aa)    
Predicted Functional Partners:
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 
 0.933
patA
Probable aminotransferase; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
  
 
 0.922
ECA4274
Similar to Yersinia pestis putative carbon-nitrogen hydrolase ypo0938 or y3324 SWALL:Q8ZHG1 (EMBL:AJ414145) (294 aa) fasta scores: E(): 2.8e-116, 93.87% id in 294 aa, and to Pseudomonas aeruginosa probable hydratase pa0293 SWALL:Q9I6J8 (EMBL:AE004467) (292 aa) fasta scores: E(): 4.5e-79, 65.05% id in 289 aa.
    
 0.911
ravA
Conserved hypothetical protein; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone; Belongs to the RavA family.
   
 
 0.648
pilV
Putative Type IV pilus prepilin protein; Similar to Escherichia coli PilV protein PilV SWALL:Q04905 (EMBL:X62169) (417 aa) fasta scores: E(): 8.8e-12, 32.47% id in 428 aa, and to Salmonella typhi PilV or sty4550 or t4250 SWALL:O51801 (EMBL:AF000001) (435 aa) fasta scores: E(): 7.5e-13, 26.49% id in 453 aa.
      
 0.544
ECA0615
Similar to Pseudomonas putida transcriptional regulator, AraC family pp2430 SWALL:AAN68042 (EMBL:AE016783) (276 aa) fasta scores: E(): 1.1e-67, 56.72% id in 275 aa, and to Pseudomonas aeruginosa probable transcriptional regulator pa2917 SWALL:Q9HZT0 (EMBL:AE004718) (278 aa) fasta scores: E(): 2.1e-63, 53.65% id in 274 aa.
   
  
 0.544
cfa7
Similar to Pseudomonas syringae type I polyketide synthase Cfa7 SWALL:Q9Z3T8 (EMBL:AF098795) (2066 aa) fasta scores: E(): 0, 52.6% id in 2091 aa, and to Streptomyces coelicolor putative type I polyketide synthase sco6275 SWALL:CAD55506 (EMBL:AL939127) (4557 aa) fasta scores: E(): 3e-183, 44.33% id in 1845 aa.
      
 0.477
cfa8B
Putative oxidoreductase; Similar to the C-terminal region of Pseudomonas syringae oxidoreductase Cfa8 SWALL:O69071 (EMBL:AF061506) (565 aa) fasta scores: E(): 6.5e-122, 74.05% id in 397 aa, and to Streptomyces lavendulae hypothetical 45.2 kDa protein SWALL:Q9X5P6 (EMBL:AF127374) (414 aa) fasta scores: E(): 2.2e-82, 52.39% id in 397 aa.
   
  
 0.476
ECA0582
Putative plasmid-related protein; Similar to Escherichia coli PemK protein pemK SWALL:PEMK_ECOLI (SWALL:P13976) (133 aa) fasta scores: E(): 3e-07, 33.33% id in 111 aa, and to Plasmid R100 plasmid stable inheritance protein pemK SWALL:BAA78898 (EMBL:AP000342) (133 aa) fasta scores: E(): 3e-07, 33.33% id in 111 aa.
     
 0.475
ECA0583
Putative plasmid-related protein; Similar to Morganella morganii PemI pemI SWALL:O52204 (EMBL:AF027767) (97 aa) fasta scores: E(): 1.7, 27.55% id in 98 aa, and to Agrobacterium tumefaciens pemi protein pemi or atu0939 or agr_c_1711 SWALL:Q8UGU6 (EMBL:AE009059) (103 aa) fasta scores: E(): 0.1, 28.73% id in 87 aa.
      
 0.475
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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