STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mltCMembrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (357 aa)    
Predicted Functional Partners:
ECA0973
Similar to Agrobacterium tumefaciens transcriptional regulator, AraC family atu0248 or agr_c_425 SWALL:Q8UIP5 (EMBL:AE008997) (365 aa) fasta scores: E(): 3.7e-23, 33.14% id in 353 aa, and to Vibrio cholerae transcriptional regulator, arac/xyls family vca0926 SWALL:Q9KL23 (EMBL:AE004420) (365 aa) fasta scores: E(): 3.5e-16, 33.69% id in 368 aa.
       0.773
ECA0975
Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family.
  
  
 0.701
mutY
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
  
    0.666
ECA0978
Putative DNA-binding protein; Similar to Escherichia coli hypothetical protein yggl or b2959 SWALL:YGGL_ECOLI (SWALL:P38521) (108 aa) fasta scores: E(): 4e-30, 66.66% id in 108 aa, and to Shigella flexneri orf, conserved hypothetical protein yggl or sf2956 SWALL:AAN44437 (EMBL:AE015308) (118 aa) fasta scores: E(): 5e-30, 66.66% id in 108 aa.
 
     0.567
trmB
Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
  
    0.522
atpI
ATP synthase protein I; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri ATP synthase protein I AtpI or UncI or b3739 or c4667 or sf3819 SWALL:ATPZ_ECOLI (SWALL:P03808) (125 aa) fasta scores: E(): 5.7e-21, 57.02% id in 121 aa.
  
     0.521
mukE
Killing factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
  
     0.514
zapC
Conserved hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
  
     0.513
fliD
Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
  
 0.458
ECA1368
Putative membrane protein; Similar to Erwinia chrysanthemi YbgE protein SWALL:Q937K8 (EMBL:AJ297885) (97 aa) fasta scores: E(): 1.7e-31, 79.16% id in 96 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri protein YbgE or b0735 or c0814 or z0903 or ecs0770 or sf0562 SWALL:YBGE_ECOLI (SWALL:P37343) (97 aa) fasta scores: E(): 4.2e-26, 63.54% id in 96 aa.
  
     0.457
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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