| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA0973 | ECA0975 | ECA0973 | ECA0975 | Similar to Agrobacterium tumefaciens transcriptional regulator, AraC family atu0248 or agr_c_425 SWALL:Q8UIP5 (EMBL:AE008997) (365 aa) fasta scores: E(): 3.7e-23, 33.14% id in 353 aa, and to Vibrio cholerae transcriptional regulator, arac/xyls family vca0926 SWALL:Q9KL23 (EMBL:AE004420) (365 aa) fasta scores: E(): 3.5e-16, 33.69% id in 368 aa. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.613 |
| ECA0973 | mltC | ECA0973 | ECA0974 | Similar to Agrobacterium tumefaciens transcriptional regulator, AraC family atu0248 or agr_c_425 SWALL:Q8UIP5 (EMBL:AE008997) (365 aa) fasta scores: E(): 3.7e-23, 33.14% id in 353 aa, and to Vibrio cholerae transcriptional regulator, arac/xyls family vca0926 SWALL:Q9KL23 (EMBL:AE004420) (365 aa) fasta scores: E(): 3.5e-16, 33.69% id in 368 aa. | Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.773 |
| ECA0973 | mutY | ECA0973 | ECA0976 | Similar to Agrobacterium tumefaciens transcriptional regulator, AraC family atu0248 or agr_c_425 SWALL:Q8UIP5 (EMBL:AE008997) (365 aa) fasta scores: E(): 3.7e-23, 33.14% id in 353 aa, and to Vibrio cholerae transcriptional regulator, arac/xyls family vca0926 SWALL:Q9KL23 (EMBL:AE004420) (365 aa) fasta scores: E(): 3.5e-16, 33.69% id in 368 aa. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.613 |
| ECA0973 | trmB | ECA0973 | ECA0977 | Similar to Agrobacterium tumefaciens transcriptional regulator, AraC family atu0248 or agr_c_425 SWALL:Q8UIP5 (EMBL:AE008997) (365 aa) fasta scores: E(): 3.7e-23, 33.14% id in 353 aa, and to Vibrio cholerae transcriptional regulator, arac/xyls family vca0926 SWALL:Q9KL23 (EMBL:AE004420) (365 aa) fasta scores: E(): 3.5e-16, 33.69% id in 368 aa. | Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.419 |
| ECA0975 | ECA0973 | ECA0975 | ECA0973 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Similar to Agrobacterium tumefaciens transcriptional regulator, AraC family atu0248 or agr_c_425 SWALL:Q8UIP5 (EMBL:AE008997) (365 aa) fasta scores: E(): 3.7e-23, 33.14% id in 353 aa, and to Vibrio cholerae transcriptional regulator, arac/xyls family vca0926 SWALL:Q9KL23 (EMBL:AE004420) (365 aa) fasta scores: E(): 3.5e-16, 33.69% id in 368 aa. | 0.613 |
| ECA0975 | cca | ECA0975 | ECA3588 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.614 |
| ECA0975 | ftsB | ECA0975 | ECA3536 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.657 |
| ECA0975 | ftsQ | ECA0975 | ECA3812 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.672 |
| ECA0975 | holA | ECA0975 | ECA1307 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Similar to Escherichia coli DNA polymerase III, delta subunit HolA or b0640 SWALL:HOLA_ECOLI (SWALL:P28630) (343 aa) fasta scores: E(): 6.2e-94, 69.79% id in 341 aa. | 0.628 |
| ECA0975 | mltC | ECA0975 | ECA0974 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.701 |
| ECA0975 | mutY | ECA0975 | ECA0976 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.818 |
| ECA0975 | smpA | ECA0975 | ECA0839 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Putative outer membrane lipopotein (small protein A); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.645 |
| ECA0975 | sspB | ECA0975 | ECA0309 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Stringent starvation protein B; Similar to Escherichia coli, and Escherichia coli O157:H7 stringent starvation protein B SspB or b3228 or z4586 or ecs4101 SWALL:SSPB_ECOLI (SWALL:P25663) (165 aa) fasta scores: E(): 3e-39, 71.42% id in 168 aa. | 0.666 |
| ECA0975 | trmB | ECA0975 | ECA0977 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.576 |
| cca | ECA0975 | ECA3588 | ECA0975 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.614 |
| cca | ftsB | ECA3588 | ECA3536 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.664 |
| cca | ftsQ | ECA3588 | ECA3812 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.598 |
| cca | holA | ECA3588 | ECA1307 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Similar to Escherichia coli DNA polymerase III, delta subunit HolA or b0640 SWALL:HOLA_ECOLI (SWALL:P28630) (343 aa) fasta scores: E(): 6.2e-94, 69.79% id in 341 aa. | 0.634 |
| cca | smpA | ECA3588 | ECA0839 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Putative outer membrane lipopotein (small protein A); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.561 |
| cca | sspB | ECA3588 | ECA0309 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Stringent starvation protein B; Similar to Escherichia coli, and Escherichia coli O157:H7 stringent starvation protein B SspB or b3228 or z4586 or ecs4101 SWALL:SSPB_ECOLI (SWALL:P25663) (165 aa) fasta scores: E(): 3e-39, 71.42% id in 168 aa. | 0.685 |