| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA0973 | ECA0975 | ECA0973 | ECA0975 | Similar to Agrobacterium tumefaciens transcriptional regulator, AraC family atu0248 or agr_c_425 SWALL:Q8UIP5 (EMBL:AE008997) (365 aa) fasta scores: E(): 3.7e-23, 33.14% id in 353 aa, and to Vibrio cholerae transcriptional regulator, arac/xyls family vca0926 SWALL:Q9KL23 (EMBL:AE004420) (365 aa) fasta scores: E(): 3.5e-16, 33.69% id in 368 aa. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.613 |
| ECA0973 | mltC | ECA0973 | ECA0974 | Similar to Agrobacterium tumefaciens transcriptional regulator, AraC family atu0248 or agr_c_425 SWALL:Q8UIP5 (EMBL:AE008997) (365 aa) fasta scores: E(): 3.7e-23, 33.14% id in 353 aa, and to Vibrio cholerae transcriptional regulator, arac/xyls family vca0926 SWALL:Q9KL23 (EMBL:AE004420) (365 aa) fasta scores: E(): 3.5e-16, 33.69% id in 368 aa. | Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.773 |
| ECA0973 | mutY | ECA0973 | ECA0976 | Similar to Agrobacterium tumefaciens transcriptional regulator, AraC family atu0248 or agr_c_425 SWALL:Q8UIP5 (EMBL:AE008997) (365 aa) fasta scores: E(): 3.7e-23, 33.14% id in 353 aa, and to Vibrio cholerae transcriptional regulator, arac/xyls family vca0926 SWALL:Q9KL23 (EMBL:AE004420) (365 aa) fasta scores: E(): 3.5e-16, 33.69% id in 368 aa. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.613 |
| ECA0973 | trmB | ECA0973 | ECA0977 | Similar to Agrobacterium tumefaciens transcriptional regulator, AraC family atu0248 or agr_c_425 SWALL:Q8UIP5 (EMBL:AE008997) (365 aa) fasta scores: E(): 3.7e-23, 33.14% id in 353 aa, and to Vibrio cholerae transcriptional regulator, arac/xyls family vca0926 SWALL:Q9KL23 (EMBL:AE004420) (365 aa) fasta scores: E(): 3.5e-16, 33.69% id in 368 aa. | Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.419 |
| ECA0975 | ECA0973 | ECA0975 | ECA0973 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Similar to Agrobacterium tumefaciens transcriptional regulator, AraC family atu0248 or agr_c_425 SWALL:Q8UIP5 (EMBL:AE008997) (365 aa) fasta scores: E(): 3.7e-23, 33.14% id in 353 aa, and to Vibrio cholerae transcriptional regulator, arac/xyls family vca0926 SWALL:Q9KL23 (EMBL:AE004420) (365 aa) fasta scores: E(): 3.5e-16, 33.69% id in 368 aa. | 0.613 |
| ECA0975 | mltC | ECA0975 | ECA0974 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.721 |
| ECA0975 | mutY | ECA0975 | ECA0976 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.820 |
| ECA0975 | trmB | ECA0975 | ECA0977 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.601 |
| dnaN | mutL | ECA4440 | ECA3936 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.905 |
| dnaN | mutY | ECA4440 | ECA0976 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.843 |
| dnaN | polA | ECA4440 | ECA0021 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.990 |
| dnaN | xthA | ECA4440 | ECA2335 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Similar to Escherichia coli exodeoxyribonuclease III XthA or Xth or b1749 SWALL:EX3_ECOLI (SWALL:P09030) (268 aa) fasta scores: E(): 1.3e-87, 76.31% id in 266 aa. | 0.857 |
| mltC | ECA0973 | ECA0974 | ECA0973 | Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | Similar to Agrobacterium tumefaciens transcriptional regulator, AraC family atu0248 or agr_c_425 SWALL:Q8UIP5 (EMBL:AE008997) (365 aa) fasta scores: E(): 3.7e-23, 33.14% id in 353 aa, and to Vibrio cholerae transcriptional regulator, arac/xyls family vca0926 SWALL:Q9KL23 (EMBL:AE004420) (365 aa) fasta scores: E(): 3.5e-16, 33.69% id in 368 aa. | 0.773 |
| mltC | ECA0975 | ECA0974 | ECA0975 | Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.721 |
| mltC | mutY | ECA0974 | ECA0976 | Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.681 |
| mltC | trmB | ECA0974 | ECA0977 | Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.545 |
| mutL | dnaN | ECA3936 | ECA4440 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.905 |
| mutL | mutY | ECA3936 | ECA0976 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.594 |
| mutL | polA | ECA3936 | ECA0021 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.769 |
| mutT | mutY | ECA3805 | ECA0976 | Similar to Escherichia coli mutator MutT protein MutT or b0099 SWALL:MUTT_ECOLI (SWALL:P08337) (129 aa) fasta scores: E(): 6.2e-23, 55.72% id in 131 aa; Belongs to the Nudix hydrolase family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.600 |
