STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutYA/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (368 aa)    
Predicted Functional Partners:
sfsA
Similar to Escherichia coli, and Escherichia coli O157:H7 sugar fermentation stimulation protein A SfsA or Sfs1 or b0146 or z0157 or ecs0150 SWALL:SFSA_ECOLI (SWALL:P18273) (234 aa) fasta scores: E(): 3e-61, 66.37% id in 232 aa; Belongs to the SfsA family.
 
    0.923
xthA
Similar to Escherichia coli exodeoxyribonuclease III XthA or Xth or b1749 SWALL:EX3_ECOLI (SWALL:P09030) (268 aa) fasta scores: E(): 1.3e-87, 76.31% id in 266 aa.
    
 0.848
ECA0975
Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family.
  
  
 0.818
mltC
Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
  
    0.666
ECA0973
Similar to Agrobacterium tumefaciens transcriptional regulator, AraC family atu0248 or agr_c_425 SWALL:Q8UIP5 (EMBL:AE008997) (365 aa) fasta scores: E(): 3.7e-23, 33.14% id in 353 aa, and to Vibrio cholerae transcriptional regulator, arac/xyls family vca0926 SWALL:Q9KL23 (EMBL:AE004420) (365 aa) fasta scores: E(): 3.5e-16, 33.69% id in 368 aa.
       0.613
trmB
Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
  
  
 0.605
birA
Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
 
  
 0.558
dnaN
DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]
   
 
 0.536
ECA0978
Putative DNA-binding protein; Similar to Escherichia coli hypothetical protein yggl or b2959 SWALL:YGGL_ECOLI (SWALL:P38521) (108 aa) fasta scores: E(): 4e-30, 66.66% id in 108 aa, and to Shigella flexneri orf, conserved hypothetical protein yggl or sf2956 SWALL:AAN44437 (EMBL:AE015308) (118 aa) fasta scores: E(): 5e-30, 66.66% id in 108 aa.
       0.528
mutS
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
 
 
 0.466
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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