STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppdBSimilar to Escherichia coli prepilin peptidase dependent protein b precursor PpdB or b2825 SWALL:PPDB_ECOLI (SWALL:P08371) (187 aa) fasta scores: E(): 3.4e-15, 27.12% id in 188 aa, and to Yersinia pestis putative prepilin peptidase dependent protein ypo1015 or y3169 SWALL:Q8ZH93 (EMBL:AJ414146) (202 aa) fasta scores: E(): 6.3e-33, 51.61% id in 186 aa. (203 aa)    
Predicted Functional Partners:
ppdA
Similar to Escherichia coli prepilin peptidase dependent protein A precursor PpdA or b2826 SWALL:PPDA_ECOLI (SWALL:P33554) (156 aa) fasta scores: E(): 5.2e-19, 40% id in 150 aa, and to Salmonella typhimurium prepilin peptidase dependent protein a, putative component in type IVpilin biogenesis ppda or stm3000 SWALL:Q8ZMB0 (EMBL:AE008837) (156 aa) fasta scores: E(): 2.7e-20, 39.35% id in 155 aa.
 
 
 0.964
outK
Similar to Erwinia carotovora general secretion pathway protein K OutK SWALL:GSPK_ERWCA (SWALL:P31706) (328 aa) fasta scores: E(): 5.7e-125, 95.12% id in 328 aa, and to Erwinia chrysanthemi general secretion pathway protein K OutK SWALL:GSPK_ERWCH (SWALL:P24690) (354 aa) fasta scores: E(): 8.7e-44, 50.69% id in 359 aa.
  
 
 0.845
ppdC
Similar to Escherichia coli prepilin peptidase dependent protein C precursor PpdC or b2823 SWALL:PPDC_ECOLI (SWALL:P08372) (107 aa) fasta scores: E(): 2.9, 24.32% id in 111 aa, and to Escherichia coli probable general secretion pathway protein i precursor GspI or b3330 SWALL:GSPI_ECOLI (SWALL:P45760) (125 aa) fasta scores: E(): 2.5, 22.4% id in 125 aa.
     
 0.837
ECA0991
Putative exported protein; Similar to Yersinia pestis putative membrane protein ypo1016 or y3168 SWALL:Q8ZH92 (EMBL:AJ414146) (156 aa) fasta scores: E(): 2.3e-18, 43.33% id in 150 aa, and to Salmonella typhi hypothetical protein Sty3136 SWALL:Q8Z415 (EMBL:AL627277) (135 aa) fasta scores: E(): 0.00037, 34.24% id in 146 aa.
  
  
 0.825
ECA1784
Conserved hypothetical protein; Similar to Salmonella typhimurium putative cytoplasmic protein ycep or stm1161 SWALL:Q8ZQ21 (EMBL:AE008750) (84 aa) fasta scores: E(): 1.1e-21, 67.85% id in 84 aa, and to Escherichia coli, and Escherichia coli O6 hypothetical protein ycep or b1060 or c1327 SWALL:YCEP_ECOLI (SWALL:P75927) (84 aa) fasta scores: E(): 1.1e-21, 67.85% id in 84 aa.
  
     0.588
recC
Exodeoxyribonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...]
       0.560
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.508
ECA2253
Putative exported protein; Similar to Yersinia pseudotuberculosis hypothetical 14.2 kDa protein orf9 SWALL:Q93AP0 (EMBL:AF418982) (124 aa) fasta scores: E(): 8.4e-19, 45.52% id in 123 aa, and to Salmonella typhimurium, and Salmonella typhi putative periplasmic protein ynfb or stm1503 or sty1560 SWALL:Q8XEU2 (EMBL:AE008765) (113 aa) fasta scores: E(): 3.1e-18, 52.52% id in 99 aa; Belongs to the UPF0482 family.
  
     0.502
pilV
Putative Type IV pilus prepilin protein; Similar to Escherichia coli PilV protein PilV SWALL:Q04905 (EMBL:X62169) (417 aa) fasta scores: E(): 8.8e-12, 32.47% id in 428 aa, and to Salmonella typhi PilV or sty4550 or t4250 SWALL:O51801 (EMBL:AF000001) (435 aa) fasta scores: E(): 7.5e-13, 26.49% id in 453 aa.
  
 
 0.487
outI
Similar to Erwinia carotovora general secretion pathway protein I precursor OutI SWALL:GSPI_ERWCA (SWALL:P31588) (121 aa) fasta scores: E(): 1.4e-44, 94.21% id in 121 aa, and to Erwinia chrysanthemi general secretion pathway protein I precursor OutI SWALL:GSPI_ERWCH (SWALL:P24688) (125 aa) fasta scores: E(): 3.3e-27, 59.32% id in 118 aa.
  
 
 0.487
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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