STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptrASimilar to Escherichia coli protease III precursor PtrA or Ptr or b2821 SWALL:PTRA_ECOLI (SWALL:P05458) (962 aa) fasta scores: E(): 0, 63.68% id in 950 aa, and to Yersinia pestis protease III ptra or ypo1019 or ptr or y3165 SWALL:Q8ZH89 (EMBL:AJ414146) (962 aa) fasta scores: E(): 0, 68.02% id in 960 aa; Belongs to the peptidase M16 family. (982 aa)    
Predicted Functional Partners:
recB
Exodeoxyribonuclease V beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repai [...]
  
  
 0.822
recD
Exodeoxyribonuclease V alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...]
  
  
 0.816
wzzE
Lipopolysaccharide biosynthesis protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family.
  
     0.733
recC
Exodeoxyribonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...]
     
 0.634
ptrB
Protease II; Similar to Escherichia coli protease II PtrB or Tlp or b1845 SWALL:PTRB_ECOLI (SWALL:P24555) (686 aa) fasta scores: E(): 2e-180, 63.93% id in 671 aa.
      
 0.631
ECA2740
Similar to Yersinia pestis hypothetical protein ypo1269 or y2914 SWALL:AAM86465 (EMBL:AJ414147) (114 aa) fasta scores: E(): 5e-30, 63.15% id in 114 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein yejg or b2181 or c2718 or sf2268 SWALL:YEJG_ECOLI (SWALL:P33917) (114 aa) fasta scores: E(): 1.4e-27, 62.28% id in 114 aa.
  
     0.622
srfC
Putative virulence factor; Similar to Salmonella typhimurium SrfC or stm1595 SWALL:Q9KIJ8 (EMBL:AF231758) (714 aa) fasta scores: E(): 4.2e-23, 30.06% id in 795 aa, and to Yersinia pestis putative virulence factor y2123 SWALL:AAM85685 (EMBL:AE013815) (846 aa) fasta scores: E(): 2.9e-65, 55.12% id in 849 aa.
  
   
 0.585
priC
Similar to Escherichia coli primosomal replication protein N'' PriC or b0467 SWALL:PRIC_ECOLI (SWALL:P23862) (174 aa) fasta scores: E(): 1.2e-14, 40.11% id in 172 aa.
  
     0.577
ECA2490
Putative maltoporin; Weakly similar to Klebsiella pneumoniae maltoporin precursor LamB SWALL:LAMB_KLEPN (SWALL:P31242) (429 aa) fasta scores: E(): 7.1e-14, 25.87% id in 398 aa, and to Escherichia coli maltoporin precursor LamB or MalB or b4036 SWALL:LAMB_ECOLI (SWALL:P02943) (446 aa) fasta scores: E(): 3.4e-05, 24.11% id in 394 aa.
      
 0.544
ppdA
Similar to Escherichia coli prepilin peptidase dependent protein A precursor PpdA or b2826 SWALL:PPDA_ECOLI (SWALL:P33554) (156 aa) fasta scores: E(): 5.2e-19, 40% id in 150 aa, and to Salmonella typhimurium prepilin peptidase dependent protein a, putative component in type IVpilin biogenesis ppda or stm3000 SWALL:Q8ZMB0 (EMBL:AE008837) (156 aa) fasta scores: E(): 2.7e-20, 39.35% id in 155 aa.
 
     0.537
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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