STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
mltAMembrane-bound lytic murein transglycosylase A precursor; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (376 aa)    
Predicted Functional Partners:
ompA
Outer-membrane protein A; Similar to Erwinia carotovora putative outer-membrane protein a precursor OmpA SWALL:Q9RM69 (EMBL:AJ249340) (367 aa) fasta scores: E(): 2.6e-120, 90.32% id in 372 aa, and to Serratia marcescens outer membrane protein a precursor OmpA SWALL:OMPA_SERMA (SWALL:P04845) (359 aa) fasta scores: E(): 4.8e-71, 75.61% id in 369 aa; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
   
 0.749
matP
Conserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
     0.649
ECA3037
Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yfbu or stm2335 or sty2565 SWALL:Q8XGJ0 (EMBL:AE008805) (164 aa) fasta scores: E(): 4.1e-58, 87.19% id in 164 aa, and to Yersinia pestis hypothetical protein Ypo2563 SWALL:Q8ZDJ9 (EMBL:AJ414152) (164 aa) fasta scores: E(): 8.8e-58, 82.92% id in 164 aa; Belongs to the UPF0304 family.
  
     0.601
ompW
Outer membrane protein W; Similar to Escherichia coli, and Shigella flexneri outer membrane protein W precursor OmpW or b1256 or sf1259 SWALL:OMPW_ECOLI (SWALL:P21364) (212 aa) fasta scores: E(): 7.2e-54, 62.26% id in 212 aa.
  
   
 0.595
ECA3465
Similar to Yersinia pestis hypothetical protein y0964 SWALL:AAM84545 (EMBL:AE013700) (421 aa) fasta scores: E(): 1.4e-127, 71.56% id in 415 aa, and to Salmonella typhimurium hypothetical protein yafa or stm0318 SWALL:YAFA_SALTY (SWALL:P37722) (414 aa) fasta scores: E(): 8.4e-120, 66.18% id in 417 aa; Belongs to the UPF0255 family.
 
     0.547
mviN
Putative virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
     
 0.531
ompH
Outer membrane protein; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm.
      
 0.530
dacD
Similar to Escherichia coli penicillin-binding protein 4 precursor [includes: d-alanyl-d- alanine carboxypeptidase; D-alanyl-D-alanine-endopeptidase] DacB or b3182 SWALL:PBP4_ECOLI (SWALL:P24228) (477 aa) fasta scores: E(): 2.2e-146, 76.31% id in 477 aa; deleted EC_number 3.4.99.-.
  
   
 0.525
ECA4240
Similar to Yersinia pestis putative membrane protein ypo3912 or y0323 SWALL:AAM83914 (EMBL:AJ414159) (135 aa) fasta scores: E(): 3e-29, 63.86% id in 119 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yijd or b3964 or c4927 or z5525 or ecs4895 SWALL:YIJD_ECOLI (SWALL:P27308) (119 aa) fasta scores: E(): 4.3e-29, 65.48% id in 113 aa.
  
     0.523
trpR
Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
  
     0.519
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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