STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1002Putative dihydrodipicolinate synthase; Similar to Escherichia coli, and Shigella flexneri dihydrodipicolinate synthase DapA or b2478 or sf2521 SWALL:DAPA_ECOLI (SWALL:P05640) (292 aa) fasta scores: E(): 2.8e-20, 30.45% id in 289 aa, and to Ralstonia solanacearum dihydrodipicolinate synthase dapa or rsc1145 or rs04756 SWALL:DAPA_RALSO (SWALL:Q8Y099) (294 aa) fasta scores: E(): 2.5e-26, 30.71% id in 280 aa; Belongs to the DapA family. (305 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
 
 0.986
thrA
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase I [includes: aspartokinase I; homoserine dehydrogenase I] thra or thra1 or thra2 or b0002 SWALL:AK1H_ECOLI (SWALL:P00561) (820 aa) fasta scores: E(): 0, 82.41% id in 819 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.954
metL
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase II MetL or MetM or b3940 SWALL:AK2H_ECOLI (SWALL:P00562) (809 aa) fasta scores: E(): 0, 83.12% id in 800 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.954
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 
 0.934
ECA3059
Similar to Shewanella violacea aspartate-semialdehyde dehydrogenase Asd SWALL:DHAS_SHEVI (SWALL:Q56734) (338 aa) fasta scores: E(): 1.3e-55, 45.1% id in 337 aa, and to Yersinia pestis putative aspartate-semialdehyde dehydrogenase Asd or ypo2765 or usg or y1598 SWALL:Q8ZD28 (EMBL:AJ414153) (336 aa) fasta scores: E(): 2.8e-104, 80.59% id in 335 aa.
 
 
 0.766
ECA1004
Probable hydrolase; Similar to Campylobacter jejuni hippurate hydrolase HipO or cj0985C SWALL:HIPO_CAMJE (SWALL:P45493) (383 aa) fasta scores: E(): 1.9e-48, 40.41% id in 386 aa, and to Rhizobium meliloti putative amidohydrolase, similar to hippurate hydrolase protein rb0783 or smb21279 SWALL:Q92VC5 (EMBL:AL603644) (389 aa) fasta scores: E(): 1.9e-65, 49.48% id in 386 aa.
 
     0.633
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.613
citF
Similar to Klebsiella pneumoniae citrate lyase alpha chain CitF SWALL:CILA_KLEPN (SWALL:P45413) (508 aa) fasta scores: E(): 1.3e-132, 67.52% id in 508 aa, and to Escherichia coli citrate lyase alpha chain citf or b0615 SWALL:CILA_ECOLI (SWALL:P75726) (510 aa) fasta scores: E(): 4.6e-131, 67.25% id in 510 aa.
   
    0.588
ECA1006
Similar to Agrobacterium tumefaciens ABC transporter, membrane spanning protein atu3435 or agr_l_2782 SWALL:Q8UAD9 (EMBL:AE009274) (341 aa) fasta scores: E(): 2.7e-69, 61.92% id in 302 aa, and to Rhizobium meliloti probable ABC transporter, permease protein ra1137 or sma2083 SWALL:Q92XV3 (EMBL:AE007299) (332 aa) fasta scores: E(): 5.3e-66, 65.92% id in 270 aa.
       0.572
ECA1007
Similar to Rhizobium meliloti probable ABC transporter, permease protein ra1138 or sma2085 SWALL:Q92XV2 (EMBL:AE007299) (328 aa) fasta scores: E(): 1.3e-81, 66.25% id in 323 aa, and to Agrobacterium tumefaciens ABC transporter, membrane spanning protein atu3434 or agr_l_2785 SWALL:Q8UAE0 (EMBL:AE009274) (347 aa) fasta scores: E(): 3.1e-79, 64.92% id in 325 aa.
       0.571
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.