STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1009Similar to Rhodobacter sphaeroides biotin sulfoxide reductase SWALL:BISC_RHOSH (SWALL:P54934) (744 aa) fasta scores: E(): 6.3e-130, 48.13% id in 725 aa, and to Escherichia coli biotin sulfoxide reductase bisc or b3551 SWALL:BISC_ECOLI (SWALL:P20099) (777 aa) fasta scores: E(): 8.5e-72, 39.01% id in 751 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (752 aa)    
Predicted Functional Partners:
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 
 0.980
birA
Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
  0.944
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
     
  0.944
ECA0914
Putative component of polysulfide reductase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri NrfC protein precursor nrfc or b4072 or z5671 or ecs5054 or sf4132 SWALL:NRFC_ECOLI (SWALL:P32708) (223 aa) fasta scores: E(): 7.3e-49, 58.66% id in 225 aa. Also similar to ECA1877 (56.444% id. in 225 aa overlap).
 
 0.900
nrfC
Nitrite reductase complex component; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri NrfC protein precursor NrfC or b4072 or z5671 or ecs5054 or sf4132 SWALL:NRFC_ECOLI (SWALL:P32708) (223 aa) fasta scores: E(): 8.4e-76, 83.4% id in 223 aa. Also similar to ECA0914 (56.444% id. in 225 aa overlap).
 
 0.899
napC
Cytochrome C-type protein; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 cytochrome C-type protein NapC or b2202 or c2739 or z3459 or ecs3091 SWALL:NAPC_ECOLI (SWALL:P33932) (200 aa) fasta scores: E(): 3.2e-61, 73.36% id in 199 aa.
 
 0.883
hybA
Hydrogenase-2 operon protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hydrogenase-2 operon protein hyba precursor HybA or b2996 or z4350 or ecs3881 or sf3043 SWALL:HYBA_ECOLI (SWALL:P37179) (328 aa) fasta scores: E(): 4.3e-93, 70.23% id in 336 aa.
 
 0.881
fdnH
Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
  
 0.860
hybB
Similar to Escherichia coli probable Ni/Fe-hydrogenase 2 B-type cytochrome subunit hybb or b2995 SWALL:HYBB_ECOLI (SWALL:P37180) (392 aa) fasta scores: E(): 8.4e-123, 73.69% id in 384 aa.
  
 0.806
ftsI
Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
 
      0.658
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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