STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcvAGlycine cleavage system transcriptional activator; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 glycine cleavage system transcriptional activator GcvA or b2808 or c3378 or z4125 or ecs3668 SWALL:GCVA_ECOLI (SWALL:P32064) (305 aa) fasta scores: E(): 1.1e-112, 91.44% id in 304 aa, and to Shigella flexneri positive regulator of gcv operon GcvA or sf2822 SWALL:AAN44309 (EMBL:AE015295) (305 aa) fasta scores: E(): 1.5e-112, 91.44% id in 304 aa; Belongs to the LysR transcriptional regulatory family. (307 aa)    
Predicted Functional Partners:
ECA1016
Putative membrane protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein ygdd ygdd or b2807 or c3377 or z4124 or ecs3667 or sf2821 SWALL:AAN44308 (EMBL:X73413) (131 aa) fasta scores: E(): 1.9e-42, 78.62% id in 131 aa, and to Salmonella typhimurium, and Salmonella typhi putative small membrane protein ygdd or stm2981 or sty3121 SWALL:Q8XEU8 (EMBL:AE008836) (131 aa) fasta scores: E(): 3.7e-41, 75.57% id in 131 aa.
  
    0.671
sftR-2
LysR-family transcriptional regulator; Similar to Pseudomonas putida SftR SWALL:Q9WWU4 (EMBL:AF126201) (304 aa) fasta scores: E(): 6.9e-58, 50.82% id in 303 aa, and to Pseudomonas sp. SDS degradation transcriptional activation protein SdsB SWALL:SDSB_PSES9 (SWALL:P52686) (306 aa) fasta scores: E(): 2.3e-29, 37.58% id in 314 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.655
ECA0916
LysR-family transcriptional regulator; Similar to Listeria innocua transcription activator of glutamate synthase operon GltC SWALL:Q92AS3 (EMBL:AL596170) (295 aa) fasta scores: E(): 8.3e-15, 25.25% id in 293 aa, and to Acinetobacter calcoaceticus ben and cat operon transcriptional regulator BenM SWALL:BENM_ACICA (SWALL:O68014) (304 aa) fasta scores: E(): 1.3e-11, 25% id in 272 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.639
ECA2642
Similar to Pseudomonas putida transcriptional regulator, LysR family pp4522 SWALL:AAN70096 (EMBL:AE016791) (297 aa) fasta scores: E(): 5.6e-24, 29.64% id in 280 aa, and to Rhizobium loti transcriptional regulator mlr6990 SWALL:Q987M7 (EMBL:AP003010) (299 aa) fasta scores: E(): 4.7e-18, 30.45% id in 266 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.623
ECA2075
LysR-family transcriptional regulator; Similar to Escherichia coli cyn operon transcriptional activator CynR or b0338 SWALL:CYNR_ECOLI (SWALL:P27111) (311 aa) fasta scores: E(): 4.5e-14, 29.51% id in 288 aa, and to Bradyrhizobium japonicum transcriptional regulatory protein bll3773 SWALL:BAC49038 (EMBL:AP005948) (312 aa) fasta scores: E(): 9e-17, 30.79% id in 302 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.610
ECA2748
Similar to Yersinia pestis hypothetical protein Ypo1261 SWALL:Q8ZGM6 (EMBL:AJ414147) (75 aa) fasta scores: E(): 4.5e-22, 85.52% id in 76 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yejl or stm2227 or sty2465 SWALL:Q8XEL6 (EMBL:AE008799) (75 aa) fasta scores: E(): 1.6e-19, 78.94% id in 76 aa; Belongs to the UPF0352 family.
  
     0.608
nac
Partial CDS. Similar to the N-terminal region of Escherichia coli nitrogen assimilation regulatory protein Nac or b1988 SWALL:NAC_ECOLI (SWALL:Q47005) (305 aa) fasta scores: E(): 1.4e-23, 77.77% id in 90 aa.
  
     0.600
ECA3202
LysR-family transcriptional regulator; Similar to Ralstonia solanacearum probable DNA-binding transcriptional regulatory transcription regulator protein rsc1196 or rs05728 SWALL:Q8Y048 (EMBL:AL646063) (306 aa) fasta scores: E(): 3.9e-42, 42.76% id in 297 aa, and to Brucella melitensis transcriptional regulatory protein, LysR family bmeii1077 SWALL:Q8YB24 (EMBL:AE009740) (294 aa) fasta scores: E(): 2.7e-38, 39.51% id in 291 aa.
  
     0.599
fadR
Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism.
  
  
 0.586
rlmM
Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
  
    0.582
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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